Anti-CD54/ICAM-1 Antibody (R6-5-D6) 

Anti-CD54/ICAM-1 Antibody (R6-5-D6) is a kind of mouse IgG2a chimeric antibody inhibitor, targeting to human CD54/ICAM-1. Anti-CD54/ICAM-1 Antibody (R6-5-D6) can block CD54 binding to its ligand Lymphocyte Function-Associated Antigen 1 (LFA-1). Anti-CD54/ICAM-1 Antibody (R6-5-D6) can be used for the researches of inflammation and immunology^[1][2].

Mouse IgG2a kappa

Mouse IgG2a kappa, Isotype Control

Human

CD54/ICAM-1

Anti-CD54/ICAM-1 Antibody (R6-5-D6) (10 μg/mL, 10 days) induces cells differentiate to Treg phenotype in human naïve CD4⁺ T cells^[1].
Anti-CD54/ICAM-1 Antibody (R6-5-D6) (2-12 μg/mL, 15 mins) reduces baseline adherence and the enhancement caused by IL-l or LPS (HY-D1056) stimulation in human umbilical vein endothelial cells (HUVEC) ^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

3383  [NCBI]

P05362

ELISA, FACS, Functional assay, Research in vivo

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

150 kDa

[Anti-CD54/ICAM-1 Antibody (R6-5-D6)]

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Williams KM, et al. Choice of resident costimulatory molecule can influence cell fate in human naïve CD4+ T cell differentiation. Cell Immunol. 2011;271(2):418-27.  [Content Brief]

  [2]. Smith CW, et al. Recognition of an endothelial determinant for CD 18-dependent human neutrophil adherence and transendothelial migration. J Clin Invest. 1988 Nov;82(5):1746-56.  [Content Brief]