1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Interleukin & Receptors
  4. IL-13 Receptor
  5. IL-13Rα2
  6. IL-13R alpha 2 Protein, Rhesus macaque (HEK293, His)

IL-13R alpha 2 Protein, Rhesus macaque (HEK293, His)

Cat. No.: HY-P78698
Handling Instructions Technical Support

IL-13R alpha 2 Protein, functioning as a monomer, exhibits high-affinity binding exclusively to interleukin-13 (IL13) without interaction with interleukin-4 (IL4). This binding selectivity indicates a unique role and specificity for IL-13R alpha 2 in mediating cellular responses to IL13, emphasizing its importance in IL13-associated cellular processes. IL-13R alpha 2 Protein, Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-13R alpha 2 Protein, Rhesus macaque (HEK293, His) is 315 a.a., with molecular weight of 45-55 kDa.

For research use only. We do not sell to patients.

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100 μg Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
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  • Biological Activity

  • Technical Parameters

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  • Documentation

Description

IL-13R alpha 2 Protein, functioning as a monomer, exhibits high-affinity binding exclusively to interleukin-13 (IL13) without interaction with interleukin-4 (IL4). This binding selectivity indicates a unique role and specificity for IL-13R alpha 2 in mediating cellular responses to IL13, emphasizing its importance in IL13-associated cellular processes. IL-13R alpha 2 Protein, Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-13R alpha 2 Protein, Rhesus macaque (HEK293, His) is 315 a.a., with molecular weight of 45-55 kDa.

Background

The IL-13R alpha 2 protein functions as a monomer with high affinity, specifically binding to interleukin-13 (IL13) but not to interleukin-4 (IL4). This selectivity in binding suggests a distinct role and specificity for IL-13R alpha 2 in mediating responses to IL13, highlighting its importance in cellular processes associated with this cytokine.

Biological Activity

Immobilized Rhesus macaque IL-13 R alpha 2 His at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-IL-13 R alpha 2 Antibody Mouse IgG1 with a linear range of 0.2-2 ng/mL.

Species

Rhesus Macaque

Source

HEK293

Tag

C-His

Accession

XP_014983540 (S26-Ther340)

Gene ID
Molecular Construction
N-term
IL-13Rα2 (S26-Ther340)
Accession # XP_014983540
His
C-term
Synonyms
IL13RA2; CD213A2; CT19; IL-13R; IL13BP
Molecular Weight

45-55 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Appearance

Lyophilized powder.

Formulation

Lyophilized a 0.22 μm filtered solution of PBS, pH 7.4. Normally trehalose is added as protectant before lyophilization.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

IL-13R alpha 2 Protein, Rhesus macaque (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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IL-13R alpha 2 Protein, Rhesus macaque (HEK293, His)
Cat. No.:
HY-P78698
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