1. Recombinant Proteins
  2. Fc Receptors Biotinylated Proteins
  3. Fc Receptor-like Proteins
  4. Fc Receptor Like 2 (FCRL2)
  5. FCRL2 Protein, Human (Biotinylated, HEK293, His)

FCRL2 Protein, Human (Biotinylated, HEK293, His)

Cat. No.: HY-P703955
Handling Instructions Technical Support

The FCRL2 protein regulates normal and neoplastic B cell development and has been shown to be involved in complex processes that control B cell maturation. Its tyrosine-phosphorylated isoform 2 interacts with PTPN6, suggesting the existence of a signaling pathway and emphasizing the role of this protein in cellular regulation. FCRL2 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived FCRL2 protein, expressed by HEK293, with C-His labeled tag.

For research use only. We do not sell to patients.

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Description

The FCRL2 protein regulates normal and neoplastic B cell development and has been shown to be involved in complex processes that control B cell maturation. Its tyrosine-phosphorylated isoform 2 interacts with PTPN6, suggesting the existence of a signaling pathway and emphasizing the role of this protein in cellular regulation. FCRL2 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived FCRL2 protein, expressed by HEK293, with C-His labeled tag.

Background

The FCRL2 protein appears to have a regulatory role in both normal and neoplastic B cell development, suggesting its involvement in the intricate processes governing B cell maturation and function. Particularly, the tyrosine-phosphorylated isoform 2 of FCRL2 is known to interact with PTPN6, indicating a potential signaling pathway and emphasizing the protein's role in cellular regulation. The specific mechanisms through which FCRL2 influences B cell development and its interaction with PTPN6 remain areas of interest, underscoring the protein's importance in immune system processes and its potential relevance in the context of B cell-related disorders.

Species

Human

Source

HEK293

Tag

C-8*His

Accession

Q96LA5-1 (L20-V401)

Gene ID

79368

Molecular Construction
N-term
FCRL2 (L20-V401)
Accession # Q96LA5-1
8*His
C-term
Protein Length

Extracellular Domain

Synonyms
FcR-like protein 2; FcRL2; FCRH2; IFGP4; IRTA4; FCRL2; CD307b; FCRH2SPAP1B; IRTA4SPAP1C; SPAP1; SPAP1A
Predicted Molecular Mass
42.7 kDa
Molecular Weight

Approximately 60-70 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

Glycosylation
Yes
Purity

Greater than 95% as determined by Tris-Bis PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

FCRL2 Protein, Human (Biotinylated, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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FCRL2 Protein, Human (Biotinylated, HEK293, His)
Cat. No.:
HY-P703955
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