1. Recombinant Proteins
  2. CD Antigens
  3. T Cell CD Proteins Dendritic Cell CD Proteins
  4. CD1a
  5. CD1A Protein, Human (HEK293, His)

The CD1A protein is a key antigen-presenting molecule that binds self and non-self lipid and glycolipid antigens and presents them to T cell receptors on natural killer T cells. CD1A, as a B2M (beta-2-microglobulin) heterodimer, plays a central role in immune surveillance and regulation. CD1A Protein, Human (HEK293, His) is the recombinant human-derived CD1A protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.

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Description

The CD1A protein is a key antigen-presenting molecule that binds self and non-self lipid and glycolipid antigens and presents them to T cell receptors on natural killer T cells. CD1A, as a B2M (beta-2-microglobulin) heterodimer, plays a central role in immune surveillance and regulation. CD1A Protein, Human (HEK293, His) is the recombinant human-derived CD1A protein, expressed by HEK293 , with C-His labeled tag.

Background

The CD1A protein stands as a pivotal antigen-presenting molecule with the unique capacity to bind both self and non-self lipid and glycolipid antigens, facilitating their presentation to T-cell receptors on natural killer T-cells. Operating as a heterodimer with B2M (beta-2-microglobulin), this protein plays a central role in immune surveillance and regulation. Its interaction with CD74 further underscores its significance in the intricate machinery of the immune system, highlighting its role in orchestrating T-cell responses to diverse antigens.

Species

Human

Source

HEK293

Tag

C-His

Accession

P06126 (D19-V300)

Gene ID

909  [NCBI]

Molecular Construction
N-term
CD1A (D19-V300)
Accession # P06126
His
C-term
Synonyms
CD1a; CD1A; CD1; FCB6; HTA1; R4; T6
Molecular Weight

48-53 kDa

Purity

Greater than 95% as determined by Tris-Bis PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

CD1A Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
CD1A Protein, Human (HEK293, His)
Cat. No.:
HY-P77624
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