Anti-Mouse CD83 Antibody (Michel-17) 

Anti-Mouse CD83 Antibody (Michel-17) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse CD83. Anti-Mouse CD83 Antibody (Michel-17) can block CD83 and inhibit T cells proliferation. Anti-Mouse CD83 Antibody (Michel-17) can be used for the researches of cancer and immunology, such as solid tumor^[1][2].

Rat IgG1 kappa

Rat IgG1 kappa, Isotype Control

Mouse

CD83

Anti-Mouse CD83 Antibody (Michel-17) (10 μg/mL, 3 days) reduceds proliferation of CD4⁺ T cells in dendritic cell: T-cell co-cultures^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mouse CD83 Antibody (Michel-17) (200 μg/mouse, i.p., every 3 days) worsens primary and secondary tumor control and diminishes overall survival companied with anti-CD70 and anti-CD86 in Hypofractionated RT/ Lenalidomide (HY-A0003) treated tumor mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

12522  [NCBI]

O88324

ELISA, FACS, Functional assay, Research in vivo

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

150 kDa

[Anti-Mouse CD83 Antibody (Michel-17)]

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Onyshchenko K, et al. Hypofractionated radiotherapy combined with lenalidomide improves systemic antitumor activity in mouse solid tumor models. Theranostics. 2024 Apr 8;14(6):2573-2588.  [Content Brief]

  [2]. Carlsson JA, et al. The Polyunsaturated Fatty Acids Arachidonic Acid and Docosahexaenoic Acid Induce Mouse Dendritic Cells Maturation but Reduce T-Cell Responses In Vitro. PLoS One. 2015 Nov 30;10(11):e0143741.  [Content Brief]