2. Immunology/Inflammation
  3. CD20
  4. Anti-Mouse CD20 Antibody (AISB12)

Anti-Mouse CD20 Antibody (AISB12) 

Cat. No.: HY-P990139 Purity: 95.00%
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Anti-Mouse CD20 Antibody (AISB12) is an anti-mouse CD20 IgG2a monoclonal antibody. Anti-Mouse CD20 Antibody (AISB12) can deplete B cells. Anti-Mouse CD20 Antibody (AISB12) can be used for research on immunology.

For research use only. We do not sell to patients.

Anti-Mouse CD20 Antibody (AISB12) Chemical Structure

Anti-Mouse CD20 Antibody (AISB12) Chemical Structure

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Description

Anti-Mouse CD20 Antibody (AISB12) is an anti-mouse CD20 IgG2a monoclonal antibody. Anti-Mouse CD20 Antibody (AISB12) can deplete B cells. Anti-Mouse CD20 Antibody (AISB12) can be used for research on immunology[1][2].

Isotype

Rat IgG2a kappa
Recommend Isotype Controls
IC50 & Target

CD20
In Vivo

Anti-Mouse CD20 Antibody (AISB12) (250 μg, i.p., 1 week before the first virus injection and continued weekly until the termination of the animals) can clear B cells and inhibit IgG antibody production in C57BL/6 mice[1].
Anti-Mouse CD20 Antibody (AISB12) (300 μg, i.p., on day 5, 8, 10, 12, 15 and 18) can clear B cells in female C57BL/6 mice bearing B16F10 tumors[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57BL/6 mice (6-12 weeks)[1]
Dosage: 250 μg
Administration: Intraperitoneal injection (i.p.), 1 week before the first virus injection and continued weekly until the termination of the animals
Result: Exhausted B cells and completely eliminates IgG antibodies, but IgM antibodies still persist.
Animal Model: 5×104 B16F10 cells injected female C57BL/6 mice (6-8 weeks)[2]
Dosage: 300 μg
Administration: Intraperitoneal injection (i.p.), on day 5, 8, 10, 12, 15 and 18
Result: Successfully cleared B cells.
Gene ID

12482  [NCBI]

Accession
Application

ELISA, FACS, Functional assay, Research in vivo
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

150 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anti-Mouse CD20 Antibody (AISB12)]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anti-Mouse CD20 Antibody (AISB12) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse CD20 Antibody (AISB12)CD20B cellsImmunologyInhibitorinhibitorinhibit

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