2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. P Glycoprotein Antibody (YA6354)

P Glycoprotein Antibody (YA6354)

Cat. No.: HY-P86662
User Guide for Antibodies Technical Support

P Glycoprotein Antibody (YA6354) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to P Glycoprotein. It can be applicated for IHC-P, IF-Tissue, IHC-F, WB assays, in the background of human, mouse, rat.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.
or Bulk Inquiry

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

P Glycoprotein Antibody (YA6354) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to P Glycoprotein. It can be applicated for IHC-P, IF-Tissue, IHC-F, WB assays, in the background of human, mouse, rat.
Background

MDR1 is a membrane transporter primarily responsible for translocating drugs and phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane (by similar). It mainly facilitates the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides, and sphingomyelins. Additionally, MDR1 functions as an energy-dependent efflux pump, contributing to reduced drug accumulation in multidrug-resistant cells.
Gene ID
SwissProt ID
Synonyms
ABC20; ABCB1; ATP binding cassette, sub family B(MDR/TAP), member 1; ATP-binding cassette sub-family B member 1; CD243; CLCS; Colchicin sensitivity; Doxorubicin resistance; GP170; MDR1; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; PGY1.
Molecular Weight

Predicted band size: 141 kDa
Purity

affinity purified.
Subcellular Location

Cell membrane; Multi-pass membrane protein.
Conjugation

Non-conjugated
Modification

Unmodified
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

IHC-P: 1:100-500; IF: 1:100-500; IHC-F: 1:100-500; WB: 1:500-2000
Application

IHC-P, IF-Tissue, IHC-F, WB
Appearance

Liquid
Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Immunogen

Recombinant Human P-glycoprotein 1 protein

Documentation
User Guide for Antibodies (1077 KB)

P Glycoprotein Antibody (YA6354) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
P Glycoprotein Antibody (YA6354)
Cat. No.:
HY-P86662
Quantity:
MCE Japan Authorized Agent:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Country or Region *

Email Address *

     

Phone Number *

 

Organization Name *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.