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  5. PD-L2 Antibody (YA1348)

PD-L2 Antibody (YA1348)

Cat. No.: HY-P81603
User Guide for Antibodies Technical Support

PD-L2 Antibody (YA1348) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PD-L2.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

PD-L2 Antibody (YA1348) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PD-L2.
Background

The PD-L2 Protein assumes a critical role in the costimulatory signal necessary for T-cell proliferation and IFNG production, operating in a PDCD1-independent manner. While its interaction with PDCD1 can inhibit T-cell proliferation by impeding cell cycle progression and cytokine production, PD-L2 itself is intricately involved in fostering these immune responses. The dynamic interplay between PD-L2 and PDCD1 highlights the regulatory mechanisms at play, emphasizing the protein's dual role in promoting or inhibiting T-cell activation based on its interactions within the immune signaling network.
Gene ID
SwissProt ID
Synonyms
PD-1 ligand 2; PD-L2; PDCD1 ligand 2; B7-DC; CD273
Molecular Weight

Predicted band size: 32 kDa; Observed band size: 50-70 kDa
Purity

Affinity Chromatography
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Immunology
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human
Dilution Ratio

FC: 1:50-1:100; ELISA: 1:10000
Application

FC, ELISA
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

Recombinant human PDL2 protein
Database

Entrez Gene: 80380 Human

SwissProt: Q9BQ51 Human

OMIM: 605723 Human

Documentation
User Guide for Antibodies (1077 KB)

PD-L2 Antibody (YA1348) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PD-L2 Antibody (YA1348)
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