Brentuximab vedotin (solution)

Cat. No.: HY-P99107A Purity: 99.73%: Data Sheet
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Brentuximab vedotin (solution) (cAC10-vcMMAE) is an antibody-drug conjugate (ADC) comprising an anti-CD30 antibody and the cytotoxic agent Monomethyl auristatin E (MMAE). Brentuximab vedotin (solution) inhibits CD30-positive cells with an IC₅₀ of 2.5 ng/mL. Brentuximab vedotin (solution) can be used for the research of relapsed and refractory Hodgkin lymphoma.

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Brentuximab vedotin (solution) Chemical Structure

CAS No. : 914088-09-8

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
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Description	Brentuximab vedotin (solution) (cAC10-vcMMAE) is an antibody-drug conjugate (ADC) comprising an anti-CD30 antibody and the cytotoxic agent Monomethyl auristatin E (MMAE). Brentuximab vedotin (solution) inhibits CD30-positive cells with an IC₅₀ of 2.5 ng/mL. Brentuximab vedotin (solution) can be used for the research of relapsed and refractory Hodgkin lymphoma^[1]^[2].
In Vitro	Brentuximab vedotin (cAC10-vcMMAE) is an antibody-drug conjugate (ADC) comprising an anti-CD30 antibody and the cytotoxic agent Monomethyl auristatin E (MMAE). Brentuximab vedotin inhibits CD30-positive cells with an IC₅₀ of 2.5 ng/mL. Brentuximab vedotin can be used for the research of relapsed and refractory Hodgkin lymphoma^[1]^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Brentuximab vedotin (solution) Related Antibodies
Molecular Weight	153000 (average)
CAS No.	914088-09-8
Appearance	Liquid
Color	Colorless to light yellow
SMILES	[Brentuximab vedotin (solution)]
Shipping	Shipping with dry ice.
Storage	-80°C, protect from light
Purity & Documentation	Purity: 99.73% Select Batch: Data Sheet (264 KB) SDS (251 KB) COA (232 KB) Others (246 KB) SEC-HPLC (245 KB) Handling Instructions (2659 KB)
References	[1]. Shea L, Mehta-Shah N. Brentuximab Vedotin in the Treatment of Peripheral T Cell Lymphoma and Cutaneous T Cell Lymphoma. Curr Hematol Malig Rep. 2020 Feb;15(1):9-19. [Content Brief] [2]. Francisco JA, et al. cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity. Blood. 2003 Aug 15;102(4):1458-65. [Content Brief]