CD49C Antibody (YA3913)

Cat. No.: HY-P84216: Data Sheet User Guide for Antibodies
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CD49C Antibody (YA3913) is a mouse-derived and non-conjugated IgG1 antibody, targeting to CD49C. It can be applicated for WB, FC, ELISA assays, in the background of human.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
Properties
Documentation

Description	CD49C Antibody (YA3913) is a mouse-derived and non-conjugated IgG1 antibody, targeting to CD49C. It can be applicated for WB, FC, ELISA assays, in the background of human.
Background	CD49C, a component of integrin alpha-3/beta-1, serves as a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin, and CSPG4. This integrin provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner, potentially participating in cell adhesion, invadopodia formation, and matrix degradation to promote invasion. Additionally, alpha-3/beta-1 may collaborate with LGALS3 to mediate CSPG4-induced endothelial cell migration. (Microbial infection context) ITGA3:ITGB1 might act as a receptor for R.delemar CotH7 in alveolar epithelial cells, possibly contributing to early-stage pulmonary mucormycosis progression. by similar: Integrin alpha-3/beta-1 functions in extracellular matrix recognition and cell migration regulation.
Gene ID	3675 [NCBI]
SwissProt ID	P26006
Synonyms	ITGA3; VL3A; FRP-2; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3
Molecular Weight	Predicted band size: 117 kDa; Observed band size: 117 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human
Dilution Ratio	WB: 1/500-1/2000; FC: 1/200-1/400; ELISA: 1/10000
Application	WB, FC, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG1
Immunogen	Purified recombinant fragment of human CD49C (AA: extra 63-248) expressed in E. Coli.
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

CD49C Antibody (YA3913) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CD49C Antibody (YA3913)

Biological Activity

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Properties

Documentation

CD49C Antibody (YA3913) Related Classifications

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