2. Immunology/Inflammation
  3. CD3
  4. Forimtamig

Forimtamig  (Synonyms: RG-6234; RO-7425781)

Cat. No.: HY-P991055
Technical Support

Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

For research use only. We do not sell to patients.

CAS No. : 2649379-96-2

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Forimtamig Related Antibodies

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Description

Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control (HY-P99001)[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
IC50 & Target

GPRC5D & CD3E
Clinical Trial
Gene ID

55507  [NCBI] & 916  [NCBI]

Accession
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
CAS No.
SMILES

[Forimtamig]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • G1-K-L with domain crossover2
Purity & Documentation
References
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Forimtamig Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Forimtamig2649379-96-2RG-6234 RO-7425781RG6234RG 6234RO7425781RO 7425781RO-7425781CD3Cluster of differentiation 3GPRC5DxCD3 T-cell-engaging bispecific antibodyInhibitorinhibitorinhibit

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