2. Immunology/Inflammation
  3. Transmembrane Glycoprotein
  4. Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1)

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) 

Cat. No.: HY-P990157 Purity: 95.00%
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Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) is an anti-mouse Thy1/CD90 IgG2a monoclonal antibody. Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) can clear T cells from the spleen and bone marrow. Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) can be used for research on immunology and inflammation conditions such as colitis.

For research use only. We do not sell to patients.

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) Chemical Structure

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) Chemical Structure

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Description

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) is an anti-mouse Thy1/CD90 IgG2a monoclonal antibody. Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) can clear T cells from the spleen and bone marrow. Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) can be used for research on immunology and inflammation conditions such as colitis[1][2][3].

IC50 & Target

Thy1/CD90
In Vitro

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) (50 μg/mL, 1 h) can remove T cells combined with 1:20 rabbit complement in antigen-presenting cells (APCs) from the spleen of mice[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) Related Antibodies
In Vivo

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) (250 μg, i.p., on days −1, 1 and 4) significantly reduces the severity of colitis in Rag2−/−Il2rg−/− mice[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: CD40 mAb induced Rag2−/−Il2rg−/− mice (8-16 weeks)[3]
Dosage: 250 μg
Administration: Intraperitoneal injection (i.p.), on days −1, 1 and 4
Result: Cleared innate lymphocytes (including NKR LTi cells, LTi like cells, and NK cells).
Relieved colitis symptoms.
Gene ID

21838  [NCBI]

Accession
Application

ELISA, FACS, Functional assay, Research in vivo
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

150 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1)]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1)Transmembrane GlycoproteinThy1/CD90T cellsimmunologycolitisInhibitorinhibitorinhibit

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