2. Recombinant Proteins
  3. CD Antigens Receptor Proteins
  4. Stem Cell CD Proteins Epithelial cell CD Proteins Cell Adhesion Molecules (CAMs)
  5. CD66e/CEACAM5 Immunoglobulin-like Cell Adhesion Molecules
  6. CD66e/CEACAM5
  7. CEACAM5 Protein, Mouse (HEK293, Fc)

The CEACAM5 protein is a key cell surface glycoprotein that promotes cell adhesion, signaling, and tumor progression. It interacts with CEACAM6 and other related molecules to support homo- and hetero-sex adhesion. CEACAM5 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CEACAM5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CEACAM5 Protein, Mouse (HEK293, Fc) is 913 a.a., with molecular weight of 135-180 kDa.

For research use only. We do not sell to patients.

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Description

The CEACAM5 protein is a key cell surface glycoprotein that promotes cell adhesion, signaling, and tumor progression. It interacts with CEACAM6 and other related molecules to support homo- and hetero-sex adhesion. CEACAM5 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CEACAM5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CEACAM5 Protein, Mouse (HEK293, Fc) is 913 a.a., with molecular weight of 135-180 kDa.
Background

The CEACAM5 protein, a cell surface glycoprotein, assumes a pivotal role in cell adhesion, intracellular signaling, and tumor progression. It facilitates both homophilic and heterophilic cell adhesion, engaging with other carcinoembryonic antigen-related cell adhesion molecules, notably CEACAM6. Functioning as an oncogene, CEACAM5 contributes to tumor progression by inducing resistance to anoikis in colorectal carcinoma cells. This glycoprotein forms homodimers, emphasizing its role as a multifaceted regulator in cellular interactions and signaling pathways, particularly influencing processes associated with cancer development and progression.
Species

Mouse
Source

HEK293
Tag

C-hFc
Accession

Q3UKK2 (Q35-E947)
Gene ID
Molecular Construction
N-term
CEACAM5 (Q35-E947)
Accession # Q3UKK2
hFc
C-term
Synonyms
CEACAM-5; CD66e; CEA; Meconium antigen 100
Molecular Weight

135-180 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

CEACAM5 Protein, Mouse (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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