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5 alpha Reductase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5 alpha Reductase (42) Aldose Reductase (6) HMG-CoA Reductase (HMGCR) (6) IFNAR (29) PGC-1α (13) TrxR (2) α-synuclein (82) 11β-HSD (4) 17β-HSD (1) 5-HT Receptor (130) AAK1 (4) Acetyl-CoA Carboxylase (2) Acyltransferase (4) ADC Cytotoxin (10) ADC Linker (7) Adenosine Receptor (7) Adenylate Cyclase (1) Adiponectin Receptor (1) Adrenergic Receptor (556) AIM2 (2) Akt (65) Aldehyde Dehydrogenase (ALDH) (5) Amino Acid Decarboxylase (2) Amino Acid Derivatives (39) Amino acid Transporter (1) Aminopeptidase (3) Aminotransferases (Transaminases) (1) AMPK (49) Amylases (61) Amyloid-β (28) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (23) Angiotensin Receptor (2) Angiotensin-converting Enzyme (ACE) (4) Antibiotic (111) Antibody-Drug Conjugates (ADCs) (2) Antifolate (8) AP-1 (5) APC (2) Apelin Receptor (APJ) (2) Apoptosis (503) Aryl Hydrocarbon Receptor (7) ASK1 (2) ATF6 (2) Atg8/LC3 (7) ATM/ATR (3) ATP Synthase (5) Aurora Kinase (6) Autophagy (291) Bacterial (218) Bcl-2 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Receptor (PAR) (1) Proteasome (15) Protein Arginine Deiminase (2) Proteolytic Enzyme (1) Proton Pump (1) PSMA (1) PTEN (1) PTHR (1) Pyroptosis (3) Pyruvate Kinase (3) RABV (1) RAD51 (3) Radionuclide-Drug Conjugates (RDCs) (4) Raf (3) RAR/RXR (80) Ras (11) Reactive Oxygen Species (104) Reference Standards (73) RET (5) REV-ERB (9) Reverse Transcriptase (6) RGS Protein (1) Ribosomal S6 Kinase (RSK) (1) RIP kinase (14) ROCK (6) ROR (7) ROS Kinase (3) Salt-inducible Kinase (SIK) (3) SARS-CoV (25) Secretin Receptor (1) Ser/Thr Kinase (1) Ser/Thr Protease (11) Serotonin Transporter (4) Serpin (1) Sex Pheromone (3) SHP2 (3) Sialyltransferase (5) Sigma Receptor (3) Sirtuin (18) Small Interfering RNA (siRNA) (2) Smo (3) SNIPERs (3) SOD (13) Sodium Channel (27) SphK (3) Src (21) STAT (27) Stearoyl-CoA Desaturase (SCD) (2) STING (8) Succinate Dehydrogenase (2) Survivin (1) Syk (3) Target Protein Ligand-Linker Conjugates (1) Taste Receptor (2) Tau Protein (9) TGF-beta/Smad (7) TGF-β Receptor (14) Thrombin (3) Thymidylate Synthase (4) Thyroid Hormone Receptor (30) Tie (1) Tim3 (1) TNF Receptor (287) TNK1 (2) Toll-like Receptor (TLR) (59) Topoisomerase (31) Trace Amine-associated Receptor (TAAR) (1) Transferrin Receptor (1) Transketolase (1) Transmembrane Glycoprotein (4) Trk Receptor (3) TRP Channel (15) TSH Receptor (2) Tyrosinase (31) Tyrosine Hydroxylase (2) VD/VDR (22) VEGFR (72) Virus Protease (3) Wee1 (2) Wnt (20) Xanthine Oxidase (5) YAP (2) Zinc Finger Protein (1) β-catenin (14) β-glucuronidase (1) γ-Glutamyl Transferase (GGT) (1)
By Research Areas:	Cancer (1966) Cardiovascular Disease (501) Endocrinology (506) Infection (485) Inflammation/Immunology (1257) Metabolic Disease (964) Neurological Disease (1162)
Click Chemistry:	Labeling and Fluorescence Imaging (1) PROTAC Synthesis (1) Azide (19) Alkynes (17)
Oligonucleotides:	A (5) Nucleosides and their Analogs (29) Thickeners (1) C (3) saRNAs (2) Flavoring Agents (1) G (3) I (2) Phospholipids (5) siRNA drugs (2) Freeze-drying Protective Agents (1) Antisense Oligonucleotides (7) Cholesterol (4) siRNAs (2) Nucleotides and their Analogs (4) T (2) U (11) Liposomal Film-forming Agents (1) Aptamers (1) CpG ODNs (28) Emulsifiers (3) Polymers (1) Sweetening Agents (2)

6300

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

466

Biochemical Assay Reagents

378

Peptides

MCE Kits

111

Inhibitory Antibodies

1243

Natural
Products

1003

Recombinant Proteins

466

Isotope-Labeled Compounds

326

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: 5 alpha Reductase Quinone Reductase Carbonyl Reductase Aldose Reductase Glutathione Reductase (GR) Dihydrofolate reductase (DHFR) HMG-CoA Reductase (HMGCR) IFNAR TrxR GSNOR α-synuclein PGC-1α VKOR

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113097

3α,7α-Dihydroxycoprostanic acid	Endogenous Metabolite	Metabolic Disease
3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid .

HY-N3994

16α,17α-Epoxyprogesterone	Drug Intermediate	Others
16α,17α-Epoxyprogesterone is an important steroid, serving as an intermediate for many hormonal drugs such as Hydrocortisone (HY-N0583) and Megestrol (HY-B1834). 16α,17α-Epoxyprogesterone can further biotransform into another significant intermediate, 11α-hydroxy-16α,17α-epoxyprogesterone, to manufacture additional compounds .

HY-113097S

3α,7α-Dihydroxycoprostanic acid-d3	Isotope-Labeled Compounds Endogenous Metabolite	Others
3α,7α-Dihydroxycoprostanic acid-d₃ is the deuterium labeled 3α,7α-Dihydroxycoprostanic acid (HY-113097) . 3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid .

HY-133971

Cholesterol 5α,6α-epoxide 5α,6α-Epoxycholesterol	Liposome	Others
Cholesterol-5α,6α-epoxide is an epoxide derivative of cholesterol formed by the enzymatic oxidation of cholesterol in the liver and other tissues. Cholesterol-5α,6α-epoxide has unique chemical properties that make it an important intermediate in the biosynthesis of bile acids, which play a key role in the digestion and absorption of dietary fats. It also has a potential physiological role in regulating cholesterol metabolism and transport, although its biological function is not fully understood.

HY-15536A

Cebranopadol ((1α,4α)stereoisomer) GRT6005 (1α,4α)stereoisomer	Opioid Receptor	Neurological Disease
Cebranopadol ((1α,4α)stereoisomer) is a stereoisomer of cebranopadol. Cebranopadol is a potent agonist activity on ORL-1.

HY-N0440R

Germacrone (Standard)	Influenza Virus NF-κB 5 alpha Reductase Keap1-Nrf2 Lactate Dehydrogenase Apoptosis	Infection Neurological Disease Inflammation/Immunology Endocrinology Cancer
Germacrone (Standard) is an analytical standard of Gemmacrone (HY-N0440). This product is intended for research and analytical applications. Germacrone (Standard) is a sesquiterpene compound with multiple biological activities. Germacrone (Standard) inhibits the H1N1 and H3N2 inﬂuenza A viruses and the inﬂuenza B virus. Germacrone (Standard) blocks the progressionof arthritis by regulating Th1/Th2 balance and inhibiting NF-κB signaling. Germacrone (Standard) can arrest the cell cycle at G0/G1 and G2/M phases and induce apoptosis in breast cancer cells. Germacrone (Standard) inhibits *5α-reductase* and has anti-androgenic effect. Germacrone (Standard) has neuroprotective functions and can be used for the study of traumatic brain injury (TBI). Germacrone (Standard) also has antioxidant activity .

HY-N15362

5α-Pregnane-3β,17α,20α-triol	Endogenous Metabolite	Endocrinology
5α-Pregnane-3β,17α,20α-triol is an endogenous steroid compound. 5α-Pregnane-3β,17α,20α-triol is the metabolite of Pregnenolone (HY-B0151) or Progesterone (HY-N0437). 5α-Pregnane-3β,17α,20α-triol is promising for research of the endocrine function of the placenta and the mechanisms related to steroid hormone metabolism during pregnancy .

HY-107850A

5α-Pregnane-3α,20α-diol Allopregnanediol	GnRH Receptor	Endocrinology
5α-Pregnane-3α,20α-diol (Allopregnanediol) is a derivative of progesterone and is one of the various steroids secreted by the ovaries of rats. 5α-Pregnane-3α,20α-diol can significantly stimulate the release of luteinizing hormone (LH) in castrated rats that have been pre-treated with estrogen, while simultaneously inhibiting the secretion of follicle-stimulating hormone (FSH) .

HY-N0176A

α-Dihydroartemisinin α-Dihydroqinghaosu; α-Artenimol	Drug Metabolite Parasite	Infection
α-Dihydroartemisinin (α-Dihydroqinghaosu; α-Artenimol) is a antimalarial agent that can be found in Artemisia annua L .

HY-113097S1

3α,7α-Dihydroxycoprostanic acid-d5	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
3α,7α-Dihydroxycoprostanic acid-d₅ is deuterium labeled 3α,7α-Dihydroxycoprostanic acid. 3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid .

HY-137393

3α,5α-Tetrahydronorethisterone	Drug Metabolite	Metabolic Disease
3α,5α-Tetrahydronorethisterone is the major urinary metabolites of Norethisterone (HY-B0554) .

HY-146225

α-Amylase/α-Glucosidase-IN-2	Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-2 (compound 5) is a potent *α-amylase* and *α-glucosidase* dual inhibitor with IC₅₀ values of 13.02, 13.09 µM for α-amylase and α-glucosidase, respectively. α-Amylase/α-Glucosidase-IN-2 has the potential for the research of diabetic complications .

HY-N2853

D-α-Tocopherylquinone α-Tocopherylquinone	Others	Cancer
D-α-Tocopherylquinone (α-Tocopherylquinone) is a quinone, can be isolated from Phaeodactylum tricornutum. D-α-Tocopherylquinone is a oxidation product of α-Tocopherol (vitamin E). D-α-Tocopherylquinone can act as an anticoagulant and as an antioxidant .

HY-147711

α-Amylase/α-Glucosidase-IN-1	Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-1 (compound 33) is a potent *α-amylase/α-glucosidase* inhibitor with IC₅₀s of 2.01, 2.09 µM for α-amylase and α-glucosidase, respectively. Kinetic studies predict that α-Amylase/α-Glucosidase-IN-1 has the potential of anti hyperglycemia .

HY-131368A

α,α-Trehalose 6-phosphate Tre6P	Endogenous Metabolite	Others
α,α-Trehalose 6-phosphate (T6P) is an endogenous metabolite. α,α-Trehalose 6-phosphate is a 6-phosphate derivative of α,α′-trehalose. α,α-Trehalose 6-phosphate is rapidly converted to the pathway end product, α,α′-trehalose, through the action of Tre6P phosphatase (T6PP) .

HY-131368

α,α-Trehalose 6-phosphate potassium Tre6P potassium	Endogenous Metabolite	Others
α,α-Trehalose 6-phosphate (Tre6P) potassium is an endogenous metabolite. α,α-Trehalose 6-phosphate is a 6-phosphate derivative of α,α′-trehalose. α,α-Trehalose 6-phosphate is rapidly converted to the pathway end product, α,α′-trehalose, through the action of Tre6P phosphatase (T6PP) .

HY-133971S

Cholesterol-5α,6α-epoxide-d7	Isotope-Labeled Compounds	Others
Cholesterol-5α,6α-epoxide-d₇ is deuterium labeled Cholesterol-5α,6α-epoxide.

HY-150857S

Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)-d4	Isotope-Labeled Compounds	Others
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers) .

HY-168961

α-Amylase/α-Glucosidase-IN-18	Amylases Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-18 (Compound 9g) is the inhibitor for *α-Amylase* and *α-Glucosidase* with IC₅₀ of 49.17 nM and 10.71 nM. α-Amylase/α-Glucosidase-IN-18 can be used in research of type 2 diabetes mellitus .

HY-172211

α-Amylase/α-Glucosidase-IN-17	Amylases Glycosidase	Metabolic Disease Cancer
α-Amylase/α-Glucosidase-IN-17 (Compound 3) is an inhibitor of *α-amylase* and *α-glucosidase, with IC₅₀* values of 14.61 μM and 25.38 μM, respectively. α-Amylase/α-Glucosidase-IN-17 has certain inhibitory activity against A549 cancer cells. α-Amylase/α-Glucosidase-IN-17 has anti-tumor and anti-diabetic effects .

HY-N10639

(1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran	Others	Others
(1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran is a sesquiterpene polyol ester. (1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran can be used for the research of various biochemical .

HY-N9487

(R)-(-)-α-Phellandrene (-)-α-Phellandrene	Bacterial	Infection Inflammation/Immunology
(R)-(-)-α-Phellandrene ((-)-α-Phellandrene) is an the (R)-(-)-stereoisomer of α-phellandrene. α-phellandrene is an orally active cyclic monoterpene that attenuates inflammatory response, and induces DNA damage .

HY-121615

α-Phellandrene alpha-Phellandrene	Insecticide Apoptosis Autophagy NO Synthase	Infection Neurological Disease Inflammation/Immunology Cancer
α-Phellandrene (alpha-Phellandrene) is an orally active monoterpenoid and insecticide. α-Phellandrene can be isolated from plant essential oils. α-Phellandrene induces Apoptosis and Autophagy. α-Phellandrene promotes cAMP signaling pathway and increases NO production. α-Phellandrene has anti-inflammatory and anticancer (sarcoma) activities. α-Phellandrene shows insecticidal activity against Lucilia cuprina L3. α-Phellandrene reduces mechanical hyperalgesia .

HY-162390

α-Amylase/α-Glucosidase-IN-11	Amylases Glycosidase	Endocrinology
α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is a isoxazolidine-isatin hybrid with significant antidiabetic activity. α-Amylase/α-Glucosidase-IN-11 competitively inhibits *α-amylase* (IC₅₀ = 30.39 μM) and *α-glucosidase* (IC₅₀ = 65.1 μM), two key digestive enzymes. α-Amylase/α-Glucosidase-IN-11 does not cross the blood-brain barrier .

HY-162169

α-Amylase/α-Glucosidase-IN-8	Amylases Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-8 (Compound 7p) is a potent dual inhibitor of *α-amylase* and *α-glucosidase, with IC₅₀s* of 10.19 and 10.33 μM, respectively. α-Amylase/α-Glucosidase-IN-8 has good anti-oxidant activity(IC₅₀ = 14.93 μM). α-Amylase/α-Glucosidase-IN-8 can be used for the research of diabetes .

HY-161469

α-Amylase/α-Glucosidase-IN-13	Amylases Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-13 (Compound 5d) is a dual inhibitor of *α-Amylase/α-Glucosidase* that can be used for diabetes research .

HY-154972

α-Amylase/α-Glucosidase-IN-3	Glycosidase Amylases	Metabolic Disease
α-Amylase/α-Glucosidase-IN-3 (Compound 17) is an *α-Amylase/α-Glucosidase* dual inhibitor, with IC₅₀s of 0.70 μM and 1.10 μM. α-Amylase/α-Glucosidase-IN-3 can be used for research of type-II diabetes mellitus .

HY-149557

α-Amylase/α-Glucosidase-IN-5	Glycosidase Amylases	Metabolic Disease
α-Amylase/α-Glucosidase-IN-5 (compound 4l) is a dual inhibitor of α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC₅₀s of 5.96 μM and 1.62 μM, respectively. α-Amylase/α-Glucosidase-IN-4 has potential antidiabetic activity .

HY-162673

α-Amylase/α-Glucosidase-IN-16	Amylases Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-16 (compound 15) is a potent dual inhibitor of *α-amylase* and *α-Glucosidase* with IC₅₀ values of 0.8 and 1.2 μM, respectively. α-Amylase/α-Glucosidase-IN-16 can be used in the study of diabetes mellitus (DM) .

HY-156380

α-Amylase/α-Glucosidase-IN-6	Amylases Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-6 (compound 5j) is a potent dual inhibitor of *α-amylase* and *α-glucosidase, with IC₅₀*s of 17.0 and 40.1 µM, respectively. α-Amylase/α-Glucosidase-IN-6 exhibits anti-hyperglycemic activities .

HY-155241

α-Amylase/α-Glucosidase-IN-4	Glycosidase Amylases	Metabolic Disease
α-Amylase/α-Glucosidase-IN-4 (compound 5) is a dual inhibitor of α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC₅₀s of 0.15 μM and 1.10 μM, respectively. α-Amylase/α-Glucosidase-IN-4 has potential antidiabetic activity .

HY-B0892S

Benzyl alcohol-α-13C-α,α-d2 Benzenemethanol-α-¹³C-α,α-d₂	Isotope-Labeled Compounds Endogenous Metabolite	Others
Benzyl alcohol-α- ¹³C-α,α-d₂ is the ¹³C-labeled Benzyl alcohol. Benzyl alcohol is an aromatic alcohol; a colorless liquid with a mild pleasant aromatic odor.

HY-N10564

8α,9α-Epoxycoleon-U-quinone	P-glycoprotein	Cancer
8α,9α-Epoxycoleon-U-quinone (compound 3) is a p-glycoprotein (P-gp) regulator that is selective for cancer cells (SI=2.0). 8α,9α-Epoxycoleon-U-quinone effectively inhibits P-gp activity in NCI-H460/R cells. 8α,9α-Epoxycoleon-U-quinone also reverses the resistance of cancer cells to Doxorubicin (DOX) (HY-15142A) and enhances the anticancer effect of DOX .

HY-133966

6α-Hydroxy-5α-cholestane 5α-Cholestane-3β,6α-diol	Reactive Oxygen Species	Others
6α-Hydroxy-5α-cholestane (5α-Cholestane-3β,6α-diol) is an oxysterol that promotes the production of superoxide anions in SK-N-BE cells at concentrations of 50 μM and 100 μM .

HY-W127508

α,α'-Dilaurin	Biochemical Assay Reagents	Others
α,α'-Dilaurin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-129953

9α,11β-Prostaglandin F2α 9α,11β-PGF2α	Endogenous Metabolite	Inflammation/Immunology
9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma .

HY-162036

α-Amylase/α-Glucosidase-IN-7	Glycosidase Amylases Cholinesterase (ChE)	Neurological Disease Metabolic Disease
α-Amylase/α-Glucosidase-IN-7 (Compound 3f) is a competitive *α-glucosidase* and *α-amylase* enzyme inhibitor with IC₅₀ values of 18.52 and 20.25 µM, respectively. α-Amylase/α-Glucosidase-IN-7 can also effectively inhibit AChE and BChE, with IC₅₀ values of 9.25 and 10.06 µM respectively. α-Amylase/α-Glucosidase-IN-7 can be used in diabetes and Alzheimer’s research .

HY-N2514

α-Lactose α-D-Lactose	Others	Others
α-Lactose (α-D-Lactose) is the major sugar present in milk. Lactose exists in the form of two anomers, α and β. The α form normally crystallizes as a monohydrate .

HY-CE00053

(24R,25R)-3Alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestan-26-oyl-CoA (24R,25R)-3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-coenzyme A	Biochemical Assay Reagents	Others
(24R,25R)-3Alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestan-26-oyl-CoA ((24R,25R)-3Alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-coenzyme A) is an acyl-CoA.

HY-CE00040

(24E)-3Alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-coenzyme A	Biochemical Assay Reagents	Others
(24E)-3Alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA ((24E)-3Alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-coenzyme A) is a 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA.

HY-129953S1

9α,11β-Prostaglandin F2α-d9 9α,11β-PGF2α-d₉	Endogenous Metabolite Isotope-Labeled Compounds	Others
9α,11β-Prostaglandin F2α-d₉ is the deuterium labeled 9α,11β-Prostaglandin F2α .

HY-W399297

Isodeoxycholic acid 7α,12α-Dihydroxycholanoic acid	Endogenous Metabolite	Metabolic Disease
Isodeoxycholic acid (7α,12α-Dihydroxycholanoic acid) is the 3β-epimer of ursodeoxycholic acid. Isodeoxycholic acid has the effect on choleresis and liver biochemistry .

HY-130529

OH-α-PVP TFA OH-α-Pyrrolidinovalerophenone TFA	Endogenous Metabolite	Metabolic Disease
OH-α-PVP (OH-α-Pyrrolidinovalerophenone ) TFA is a metabolite of α-pyrrolidinovalerophenone. α-pyrrolidinovalerophenone is a synthetic stimulant of the cathinone class .

HY-172622

α-Amylase/α-Glucosidase-IN-19	Amylases Glycosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-19 (compound 10) is a dual inhibitor of α-amylase /α-glucosidase (IC₅₀= 170.7 μM and 60.37 μM, respectively) .

HY-P5859

α-Pompilidotoxin α-PMTX	Biochemical Assay Reagents	Neurological Disease
α-Pompilidotoxin (α-PMTX) is a neurotoxin that can be obtained from the venom of Anoplius safnariensis. α-Pompilidotoxin reversibly and dose-dependently enhances excitatory postsynaptic currents (EPSCs). α-Pompilidotoxin is a useful tool in the field of neuroscience research .

HY-170056

2α-Methyl-5α-androstan-17-one-3α-glucuronide	Drug Metabolite	Endocrinology
2α-Methyl-5α-androstan-17-one-3α-glucuronide is a metabolite of Drostanolone .

HY-114656

Dihydro-PGF1α Dihydroprostaglandin F1α	Drug Metabolite	Endocrinology
Dihydro-PGF1α is a potential metabolite of PGF1α .

HY-129953S

9α,11β-Prostaglandin F2α-d4 9α,11β-PGF2α-d-d₄	Isotope-Labeled Compounds Endogenous Metabolite	Inflammation/Immunology
9α,11β-Prostaglandin F2α-d4 is a deuterated labeled 9α,11β-Prostaglandin F2α . 9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma .

HY-N1467

(-)-α-Terpineol (S)-α-Terpineol	Others	Others
(-)-α-Terpineol ((S)-α-Terpineol), a monoterpene compound, is one of compounds in Melaleuca alternifolia. (-)-α-Terpineol has antioxidant and anti-inflammatory activities .

HY-P9970A

Infliximab (Anti-TNF-α) Avakine (Anti-TNF-α); CT-P13 (Anti-TNF-α)	TNF Receptor	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Infliximab (Anti-TNF-α) (Avakine (Anti-TNF-α)) is a chimeric monoclonal IgG1 antibody that specifically binds to *TNF-α. Infliximab (Anti-TNF-α) prevents the interaction of TNF-α* with TNF-α receptor (TNFR1 and TNFR2). Infliximab (Anti-TNF-α) has the potential for autoimmune, chronic inflammatory diseases and diabetic neuropathy research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113097

3α,7α-Dihydroxycoprostanic acid	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid .

HY-137393

3α,5α-Tetrahydronorethisterone	Triterpenes Structural Classification Terpenoids Source classification Endogenous metabolite	Drug Metabolite
3α,5α-Tetrahydronorethisterone is the major urinary metabolites of Norethisterone (HY-B0554) .

HY-N2853

D-α-Tocopherylquinone α-Tocopherylquinone	Quinones Microorganisms Classification of Application Fields Source classification Benzene Quinones Disease Research Fields Cancer	Others
D-α-Tocopherylquinone (α-Tocopherylquinone) is a quinone, can be isolated from Phaeodactylum tricornutum. D-α-Tocopherylquinone is a oxidation product of α-Tocopherol (vitamin E). D-α-Tocopherylquinone can act as an anticoagulant and as an antioxidant .

HY-131368

α,α-Trehalose 6-phosphate potassium Tre6P potassium	Structural Classification Arabidopsis thaliana (L.) Heynh. Source classification Plants Brassicaceae Saccharides	Endogenous Metabolite
α,α-Trehalose 6-phosphate (Tre6P) potassium is an endogenous metabolite. α,α-Trehalose 6-phosphate is a 6-phosphate derivative of α,α′-trehalose. α,α-Trehalose 6-phosphate is rapidly converted to the pathway end product, α,α′-trehalose, through the action of Tre6P phosphatase (T6PP) .

HY-N9487

(R)-(-)-α-Phellandrene (-)-α-Phellandrene	Structural Classification Other Monoterpenes Terpenoids Plants Schinus terebinthifolius Raddi Anacardiaceae	Bacterial
(R)-(-)-α-Phellandrene ((-)-α-Phellandrene) is an the (R)-(-)-stereoisomer of α-phellandrene. α-phellandrene is an orally active cyclic monoterpene that attenuates inflammatory response, and induces DNA damage .

HY-121615

α-Phellandrene alpha-Phellandrene	Melaleuca alternifolia Structural Classification Other Monoterpenes Terpenoids Source classification Myrtaceae Plants	Insecticide Apoptosis Autophagy NO Synthase
α-Phellandrene (alpha-Phellandrene) is an orally active monoterpenoid and insecticide. α-Phellandrene can be isolated from plant essential oils. α-Phellandrene induces Apoptosis and Autophagy. α-Phellandrene promotes cAMP signaling pathway and increases NO production. α-Phellandrene has anti-inflammatory and anticancer (sarcoma) activities. α-Phellandrene shows insecticidal activity against Lucilia cuprina L3. α-Phellandrene reduces mechanical hyperalgesia .

HY-N0440R

Germacrone (Standard)	Structural Classification Terpenoids Sesquiterpenes Source classification Plants Curcuma longa Zingiberaceae	Influenza Virus NF-κB 5 alpha Reductase Keap1-Nrf2 Lactate Dehydrogenase Apoptosis
Germacrone (Standard) is an analytical standard of Gemmacrone (HY-N0440). This product is intended for research and analytical applications. Germacrone (Standard) is a sesquiterpene compound with multiple biological activities. Germacrone (Standard) inhibits the H1N1 and H3N2 inﬂuenza A viruses and the inﬂuenza B virus. Germacrone (Standard) blocks the progressionof arthritis by regulating Th1/Th2 balance and inhibiting NF-κB signaling. Germacrone (Standard) can arrest the cell cycle at G0/G1 and G2/M phases and induce apoptosis in breast cancer cells. Germacrone (Standard) inhibits *5α-reductase* and has anti-androgenic effect. Germacrone (Standard) has neuroprotective functions and can be used for the study of traumatic brain injury (TBI). Germacrone (Standard) also has antioxidant activity .

HY-N15362

5α-Pregnane-3β,17α,20α-triol	Structural Classification Animals Source classification Steroids	Endogenous Metabolite
5α-Pregnane-3β,17α,20α-triol is an endogenous steroid compound. 5α-Pregnane-3β,17α,20α-triol is the metabolite of Pregnenolone (HY-B0151) or Progesterone (HY-N0437). 5α-Pregnane-3β,17α,20α-triol is promising for research of the endocrine function of the placenta and the mechanisms related to steroid hormone metabolism during pregnancy .

HY-N0176A

α-Dihydroartemisinin α-Dihydroqinghaosu; α-Artenimol	Structural Classification Terpenoids Sesquiterpenes Source classification Artemisia carvifolia Buch.-Ham. ex Roxb. Plants Compositae	Drug Metabolite Parasite
α-Dihydroartemisinin (α-Dihydroqinghaosu; α-Artenimol) is a antimalarial agent that can be found in Artemisia annua L .

HY-131368A

α,α-Trehalose 6-phosphate Tre6P	Structural Classification Human Gut Microbiota Metabolites Polysaccharides Microorganisms Source classification Endogenous metabolite Saccharides	Endogenous Metabolite
α,α-Trehalose 6-phosphate (T6P) is an endogenous metabolite. α,α-Trehalose 6-phosphate is a 6-phosphate derivative of α,α′-trehalose. α,α-Trehalose 6-phosphate is rapidly converted to the pathway end product, α,α′-trehalose, through the action of Tre6P phosphatase (T6PP) .

HY-N10564

8α,9α-Epoxycoleon-U-quinone	Structural Classification Ketones, Aldehydes, Acids Labiatae Smallanthus uvedalia (Linnaeus) Mackenzie Plants	P-glycoprotein
8α,9α-Epoxycoleon-U-quinone (compound 3) is a p-glycoprotein (P-gp) regulator that is selective for cancer cells (SI=2.0). 8α,9α-Epoxycoleon-U-quinone effectively inhibits P-gp activity in NCI-H460/R cells. 8α,9α-Epoxycoleon-U-quinone also reverses the resistance of cancer cells to Doxorubicin (DOX) (HY-15142A) and enhances the anticancer effect of DOX .

HY-129953

9α,11β-Prostaglandin F2α 9α,11β-PGF2α	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma .

HY-N2514

α-Lactose α-D-Lactose	Structural Classification Polysaccharides Animals Classification of Application Fields Source classification Other Diseases Disease Research Fields Saccharides	Others
α-Lactose (α-D-Lactose) is the major sugar present in milk. Lactose exists in the form of two anomers, α and β. The α form normally crystallizes as a monohydrate .

HY-W399297

Isodeoxycholic acid 7α,12α-Dihydroxycholanoic acid	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Isodeoxycholic acid (7α,12α-Dihydroxycholanoic acid) is the 3β-epimer of ursodeoxycholic acid. Isodeoxycholic acid has the effect on choleresis and liver biochemistry .

HY-N1467

(-)-α-Terpineol (S)-α-Terpineol	Other Terpenoids Melaleuca alternifolia Structural Classification Classification of Application Fields Terpenoids Source classification Other Diseases Myrtaceae Plants Disease Research Fields	Others
(-)-α-Terpineol ((S)-α-Terpineol), a monoterpene compound, is one of compounds in Melaleuca alternifolia. (-)-α-Terpineol has antioxidant and anti-inflammatory activities .

HY-N0611

alpha-Boswellic acid α-Boswellic acid	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Boswellia serrata Plants Burseraceae Inflammation/Immunology Disease Research Fields	Others
alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research .

HY-N8459

α-Cembrenediol α-CBD	Structural Classification Natural Products Nicotiana tabacum L. Source classification Plants Solanaceae	EBV
α-Cembrenediol is a potent inhibitor of *EBV*.α-Cembrenediol inhibits the early antigen of the Epstein-Bar virus. α-Cembrenediol also has anti-tumour activity .

HY-N9960

α-Isopropylmalate α-IPM	Structural Classification Microorganisms Animals Ketones, Aldehydes, Acids Source classification	Drug Intermediate
α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast .

HY-N2766

*8alpha-Hydroxy-alpha-gurjunene*	Structural Classification Terpenoids Sesquiterpenes Source classification Sarcandra glabra (Thunb.) Nakai Chloranthaceae Plants	Others
8alpha-Hydroxy-alpha-gurjunene is a Sesquiterpenoids product that can be isolated from the herbs of Sarcandra glabra .

HY-N9083

8α-Hydroxy-α-gurjunene	Structural Classification Flavonoids Leguminosae Source classification Plants Sophora tomentosa L.	Others
8α-Hydroxy-α-gurjunene is a Flavonoids product that can be isolated from the aerial parts of Sophora tomentosa L. .

HY-N9960R

α-Isopropylmalate (Standard) α-IPM (Standard)	Structural Classification Microorganisms Animals Ketones, Aldehydes, Acids Source classification	Others
α-Isopropylmalate (Standard) is the analytical standard of α-Isopropylmalate. This product is intended for research and analytical applications. α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast .

HY-W087904

α-Lactose hydrate α-D-Lactose hydrate	Structural Classification Polysaccharides Animals Source classification Saccharides	Endogenous Metabolite
α-Lactose (hydrate) (α-D-Lactose (hydrate)) is the principal carbohydrate in the milk of most mammals. α-Lactose (hydrate) consists of glucose and galactose and exists in the form of two anomers, α and β. α-Lactose (hydrate) has many uses in the food and pharmaceutical industries, such as a free-flowing or agglomerating agent, a diluent for pigments, flavors, or enzymes .

HY-N8847

α-Ionone alpha-Ionone	Source classification Asteraceae Sonchus erzincanicusV.A.Matthews Plants	Hippo (MST) YAP Olfactory Receptor Apoptosis
α-Ionone (alpha-Ionone) is an activator of the olfactory receptor OR10A6. α-Ionone induces apoptosis by activating OR10A6 and increasing the phosphorylation of the LATS-YAP-TAZ signaling axis in the Hippo pathway. α-Ionone can inhibit tumor formation both in vivo and in vitro .

HY-N0683

α-Vitamin E 10+ Cited Publications (+)-α-Tocopherol; D-α-Tocopherol	Infection Structural Classification Monophenols Classification of Application Fields Source classification Moisture Phenols Cosmetic Research Endogenous metabolite Disease Research Fields Cancer Food Research	Bacterial Influenza Virus Reactive Oxygen Species Ferroptosis Endogenous Metabolite
α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant .

HY-133890A

Tauro-α-muricholic acid sodium 2 Publications Verification T-α-MCA sodium	Structural Classification Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite FXR
Tauro-α-muricholic acid (T-α-MCA) sodium is a FXR (Farnesoid X receptor) antagonist (IC₅₀=28μM). Tauro-α-muricholic acid sodium is also a endogenous metabolite that can be found in cecal .

HY-133890

Tauro-α-muricholic acid T-α-MCA	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite FXR
Tauro-alpha-muricholic acid (T-alpha-MCA) is a bile acid that belongs to a class of compounds that are synthesized in the liver and play an important role in the digestive process. Tauro-α-muricholic acid activates Farni X receptors (FXR) which are involved in the regulation of bile acid synthesis, metabolism and transport. Tauro-alpha-muricholic acid can be used in the study of metabolic syndrome and cardiovascular disease .

HY-N1720

2α,3α,24-Trihydroxyolean-12-en-28-oic acid	Triterpenes Classification of Application Fields Terpenoids Pyrus pashia Buch.-Ham. ex D. Don Source classification Rosaceae Other Diseases Plants Disease Research Fields	Others
2α,3α,24-Trihydroxyolean-12-en-28-oic acid (compound 5) is a terpenoid that is isolated from the branches and leaves of Pyrus pashia. 2α,3α,24-Trihydroxyolean-12-en-28-oic acid shows cytotoxic activity .

HY-W020044

*DL-alpha-Tocopherol* 5 Publications Verification DL-α-Tocopherol	Structural Classification Duchesnea indica (Andr.) Focke Monophenols Classification of Application Fields Source classification Rosaceae Other Diseases Phenols Plants Disease Research Fields	Ferroptosis DNA/RNA Synthesis Apoptosis
DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .

HY-116757

(±)-α-CMBHC	Cardiovascular Disease Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(±)-α-CMBHC is a metabolite of α-Tocopherol .

HY-N0683A

rel-α-Vitamin E rel-D-α-Tocopherol	Structural Classification Natural Products Monophenols other families Classification of Application Fields Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Bacterial Influenza Virus Reactive Oxygen Species Endogenous Metabolite
rel-α-Vitamin E (rel-D-α-Tocopherol) is a vitamin with antioxidant properties and also a mixture .

HY-N2018

α-D-Xylose α-D-Xylopyranose	Structural Classification Source classification Plants Endogenous metabolite Saccharides Monosaccharides	Endogenous Metabolite
α-D-Xylose (α-D-Xylopyranose) is a basic component of the five-carbon fraction of biomass and a precursor of hemicellulose. α-D-Xylose participates in a variety of enzyme-catalyzed reactions, which in turn participate in a variety of metabolic pathways. In addition, α-D-Xylose is also used in tanning, dyeing and as a diabetic food .

HY-N9699

8α-Hydroxyhirsutinolide	Structural Classification Terpenoids Sesquiterpenes Source classification Plants Compositae Vachellia nilotica (L.) P. J. H. Hurter & Mabb.	NF-κB
8α-Hydroxyhirsutinolide is a sesquiterpene lactone. 8α-Hydroxyhirsutinolide inhibits TNF-α-induced NF-κB activity (IC₅₀: 1.9 μM) and NO production. 8α-Hydroxyhirsutinolide can be isolated from Vernonia cinerea .

HY-N0700

alpha-Asarone α-Asarone; trans-Asarone	Acorus tatarinowii Schott Structural Classification Simple Phenylpropanols Araceae Source classification Phenylpropanoids Plants	GABA Receptor
alpha-Asarone (α-Asarone) is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.

HY-N8745

α-Peltatin	Structural Classification Podophyllum peltatum L. Source classification Lignans Phenylpropanoids Plants Berberidaceae	Fungal
α-Peltatin is an aryl lignan. α-Peltatin has anticancer and antifungal activity. α-Peltatin inhibits DNA topoisomerase and tubulin polymerization .

HY-B1513

α-Cyclodextrin 2 Publications Verification	Structural Classification Zea mays L. Polysaccharides Classification of Application Fields Gramineae Source classification Other Diseases Plants Disease Research Fields Saccharides	Microtubule/Tubulin SARS-CoV
α-Cyclodextrin (α-CD) is a soluble fiber derived from corn. α-Cyclodextrin can deplete sphingolipids and phospholipids from cell membranes. α-Cyclodextrin interacts with tubulin. α-Cyclodextrin improves defenses against SARS-CoV-2 infection. α-Cyclodextrin enhances the anticancer efficacy of Crcumin (HY-N0005) against breast, lung and cervical cancer. α-Cyclodextrin has beneficial effects on body weight and blood lipids .

HY-N0255

alpha-Hederin 1 Publications Verification α-Hederin	Triterpenes Structural Classification Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields Araliaceae	Apoptosis
alpha-Hederin (α-Hederin), a monodesmosidic triterpenoid saponin, exhibits promising antitumor potential against a variety of human cancer cell lines. alpha-Hederin could inhibit the proliferation and induce apoptosis of gastric cancer accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway .

HY-N8908

2α,9α,11-Trihydroxy-6-oxodrim-7-ene	Other Terpenoids Structural Classification Microorganisms Terpenoids Source classification	Others
2α,9α,11-Trihydroxy-6-oxodrim-7-ene is a natural product that can be isolated from the culture medium of the marine-derived fungus Aspergillus insuetus .

HY-113962

7α,25-Dihydroxycholesterol 2 Publications Verification 7α,25-OHC	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	EBI2/GPR183 Endogenous Metabolite
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC₅₀=140 pM; K_d=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells .

HY-113269

alpha-CEHC	Microorganisms Source classification	Drug Metabolite
alpha-CEHC is a water-soluble metabolite of alpha-tocopherol (α-TOH) with potential antioxidant activity. alpha-CEHC slightly inhibits macrophage-induced low-density lipoprotein (LDL) oxidation, and its inhibitory potency is concentration-dependent .

HY-N0492

α-Lipoic Acid 5+ Cited Publications Thioctic acid; (±)-α-Lipoic acid; DL-α-Lipoic acid	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis
α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

HY-N0492A

α-Lipoic Acid sodium 5+ Cited Publications Thioctic acid sodium; (±)-α-Lipoic acid sodium; DL-α-Lipoic acid sodium	Infection Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Cancer	NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis
α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

HY-B2193

α-Amylase 1 Publications Verification	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields	Amylases
α-Amylase is a hydrolase enzyme that catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose.

HY-N7563

α-Toxicarol	Structural Classification Flavonoids Leguminosae Source classification Derris trifoliata Lour. Plants Other Flavonoids	EBV
α-Toxicarol is a potent inhibitor of *EBV*.α-Toxicarol significantly inhibits mouse skin tumor in vivo. α-Toxicarol inhibits the TPA-induced EBV-EA activation .

HY-N0492R

α-Lipoic Acid (Standard) 5+ Cited Publications Thioctic acid (Standard); (±)-α-Lipoic acid (Standard); DL-α-Lipoic acid (Standard)	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis
α-Lipoic Acid (Standard) is the analytical standard of α-Lipoic Acid. This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

HY-N0710

alpha-Cyperone 2 Publications Verification α-Cyperone; (+)-α-Cyperone	Structural Classification other families Classification of Application Fields Terpenoids Sesquiterpenes Source classification Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.

HY-N0328R

alpha-Mangostin (Standard) 5+ Cited Publications α-Mangostin (Standard)	Structural Classification other families Xanthones Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	Fungal Reactive Oxygen Species Bacterial Apoptosis Virus Protease
alpha-Mangostin (Standard) is the analytical standard of alpha-Mangostin. This product is intended for research and analytical applications. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-N0611R

alpha-Boswellic acid (Standard)	Triterpenes Structural Classification Terpenoids Source classification Boswellia serrata Plants Burseraceae	Others
alpha-Boswellic acid (Standard) is the analytical standard of alpha-Boswellic acid. This product is intended for research and analytical applications. alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research .

HY-117845

Citreamicin alpha LL-E19085α	Structural Classification Microorganisms Antibiotics Source classification	Bacterial Antibiotic
Citreamicin alpha (LL-E 19085-alpha) is an antibiotic whose in vitro antimicrobial activity against 429 clinical isolates of Gram-positive cocci has been tested by the agar dilution method. These microorganisms included 313 strains of Staphylococci and 116 strains of Streptococci. The in vitro activity of Citreamicin alpha was compared with that of ampicillin, amoxicillin, ceftriaxone, erythromycin, and vancomycin. For Staphylococci, the MIC values of Citreamicin alpha ranged from 0.12-4.0 μg/ml, and for Streptococcus pyogenes of the genus Streptococcus, it was 0.03-0.12 μg/ml. However, enterococci were relatively resistant, requiring 2.0 μg/ml of the agent to inhibit 64% of the 62 tested strains. The in vitro activity of this antibiotic was much better than that of ampicillin, amoxicillin, ceftriaxone, and erythromycin, but comparable or slightly inferior to that of vancomycin.

HY-N0492AR

α-Lipoic Acid sodium (Standard) Thioctic acid sodium (Standard); (±)-α-Lipoic acid sodium (Standard); DL-α-Lipoic acid sodium (Standard)	Natural Products Source classification Endogenous metabolite	NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis
α-Lipoic Acid (sodium) (Standard) is the analytical standard of α-Lipoic Acid (sodium). This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation[1][2][3]. α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells[4]. α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1[5].

HY-N0700R

alpha-Asarone (Standard)	Acorus tatarinowii Schott Structural Classification Simple Phenylpropanols Araceae Source classification Phenylpropanoids Plants	GABA Receptor
alpha-Asarone (Standard) is the analytical standard of alpha-Asarone. This product is intended for research and analytical applications. alpha-Asarone (α-Asarone) is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.

Cat. No.	Product Name	Chemical Structure

HY-113097S

3α,7α-Dihydroxycoprostanic acid-d3
3α,7α-Dihydroxycoprostanic acid-d₃ is the deuterium labeled 3α,7α-Dihydroxycoprostanic acid (HY-113097) . 3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid .

HY-133971S

Cholesterol-5α,6α-epoxide-d7
Cholesterol-5α,6α-epoxide-d₇ is deuterium labeled Cholesterol-5α,6α-epoxide.

HY-133966S

6α-Hydroxy-5α-cholestane-d7
6α-Hydroxy-5α-cholestane-d₇ is deuterium labeled 6α-Hydroxy-5α-cholestane.

HY-113097S1

3α,7α-Dihydroxycoprostanic acid-d5
3α,7α-Dihydroxycoprostanic acid-d₅ is deuterium labeled 3α,7α-Dihydroxycoprostanic acid. 3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid .

HY-150857S

Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)-d4
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers) .

HY-B0892S

Benzyl alcohol-α-13C-α,α-d2
Benzyl alcohol-α- ¹³C-α,α-d₂ is the ¹³C-labeled Benzyl alcohol. Benzyl alcohol is an aromatic alcohol; a colorless liquid with a mild pleasant aromatic odor.

HY-129953S1

9α,11β-Prostaglandin F2α-d9
9α,11β-Prostaglandin F2α-d₉ is the deuterium labeled 9α,11β-Prostaglandin F2α .

HY-129953S

9α,11β-Prostaglandin F2α-d4
9α,11β-Prostaglandin F2α-d4 is a deuterated labeled 9α,11β-Prostaglandin F2α . 9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma .

HY-167584S

3α,12α-Dihydroxy-5β-cholestanoic acid-d5
3α,12α-Dihydroxy-5β-cholestanoic acid-d₅ is deuterium labeled 3α,12α-Dihydroxy-5β-cholestanoic acid .

HY-Y0149S

3,4-Dimethoxyphenylacetonitrile-α,α-d2
3,4-Dimethoxyphenylacetonitrile-α,α-d₂ is the deuterium labeled (3,4-Dimethoxyphenyl)acetonitrile .

HY-B1204S

Histamine-α,α,β,β-d4 dihydrochloride
Histamine-α,α,β,β-d₄ (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

HY-113962S

7α,25-Dihydroxycholesterol-d6
7α,25-Dihydroxycholesterol-d₆ is deuterium labeled 7α,25-Dihydroxycholesterol. 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly

HY-N0683S6

α-Vitamin E-d11
α-Vitamin E-d11 ((+)-α-Tocopherol-d11) is the deuterium labeled α-Vitamin E (HY-N0683). α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant .

HY-B1278S1

α-Tocopherol-d6 acetate
α-Tocopherol-d₆ (acetate) is the deuterium labeled D-α-Tocopherol acetate. D-α-Tocopherol acetate (D-Vitamin E acetate) can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine .

HY-123489S

3α,21-Dihydroxy-5α-pregnan-20-one-d3
3α,21-Dihydroxy-5α-pregnan-20-one-d₃ is the deuterium labeled 3α,21-Dihydroxy-5α-pregnan-20-one. 3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro.

HY-146788S

7α,27-Dihydroxycholesterol-d6
7α,27-Dihydroxycholesterol-d₆ is deuterium labeled 7α,27-Dihydroxycholesterol.

HY-113031S

16α-Hydroxydehydroepiandrosterone-d6
16α-Hydroxydehydroepiandrosterone-d₆ (16α-Hydroxy-DHEA-d₆) is the deuterium labeled 16α-Hydroxydehydroepiandrosterone .

HY-W020044S1

*DL-alpha-Tocopherol-d9*
DL-alpha-Tocopherol-d₉ is the deuterium labeled DL-alpha-Tocopherol . DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .

HY-W014118S

α-Hexylcinnamaldehyde-d5
α-Hexylcinnamaldehyde-d₅ is deuterated labeled α-Hexylcinnamaldehyde (HY-W014118). α-Hexylcinnamaldehyde, a compound derived from Cinnamaldehyde. α-Hexylcinnamaldehyde has the potential antimutagenic and chemosensitizing properties. α-Hexylcinnamaldehyde is widely used as an ingredient in many personal care, and as an additive in food and the pharmaceutical industry .

HY-N7148S

α-Vitamin E-d6
α-Vitamin E-d₆ is the deuterium labeled α-Vitamin E .

HY-113031S1

16α-Hydroxydehydroepiandrosterone-d5
16α-Hydroxydehydroepiandrosterone-d₅ (16α-Hydroxy-DHEA-d₅) is the deuterium labeled 16α-Hydroxydehydroepiandrosterone (HY-113031) .

HY-133890AS

Tauro-α-muricholic acid-d4 sodium
Tauro-α-muricholic acid-d₄ (sodium) is the deuterium labeled Tauro-α-muricholic acid sodium .

HY-N6710S

α-Zearalenol-d4
α-Zearalenol-d4 is a deuterated labeled α-Zearalenol . α-Zearalenol is a Mycotoxin with high affinity for the estrogen receptors (ER), α-Zearalenol is the derivative of zearalenone (ZEN), causes reproductive disorders in animals, due to its xenoestrogenic effects .

HY-W654353

Tauro-α-muricholic acid-d4-1 sodium
Tauro-α-muricholic acid-d₄-1 (sodium) is deuterium labeled Tauro-α-muricholic acid (sodium). Tauro-α-muricholic acid (T-α-MCA) sodium is a FXR (Farnesoid X receptor) antagonist (IC₅₀=28μM). Tauro-α-muricholic acid sodium is also a endogenous metabolite that can be found in cecal .

HY-N7264S

7α-Hydroxycholesterol-d7
7α-Hydroxycholesterol-d₇ is the deuterium labeled 7α-Hydroxycholesterol. 7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation .

HY-132649S

α-Cholestane-d4
α-Cholestane-d₄ is the deuterium labeled α-Cholestane .

HY-134670S1

α-Hydroxymetoprolol-d7
α-Hydroxymetoprolol-d₇ is the deuterium labeled α-Hydroxymetoprolol .

HY-Y0245S

α-Cyanopyridine-d4
α-Cyanopyridine-d₄ is the deuterium labeled α-Cyanopyridine .

HY-N5142S1

α-Terpineol-d6

α-Terpineol-d₆ is deuterated labeled α-Terpineol (HY-N5142). α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .

HY-128417S

alpha-D-glucose-d12
alpha-D-glucose-d₁₂ is the deuterium labeled alpha-D-glucose. alpha-D-glucose is an endogenous metabolite.

HY-128417S1

Alpha-D-glucose-13C
Alpha-D-glucose- ¹³C is the ¹³C labeled alpha-D-glucose. alpha-D-glucose is an endogenous metabolite .

HY-128417S3

alpha-D-glucose-d7
alpha-D-glucose-d₇ is the deuterium labeled alpha-D-glucose . alpha-D-glucose is an endogenous metabolite.

HY-133970S

5α-Cholestane-d6
5α-Cholestane-d₆ is the deuterium labeled 5α-Cholestane .

HY-133970S1

5α-Cholestane-d2
5α-Cholestane-d₂ is the deuterium labeled 5α-Cholestane .

HY-118566S

5α-Androstenone-d4
5α-Androstenone-d₄ is the deuterium labeled 5α-Androstenone .

HY-151892S

Glimepiride-d4(phenylethyl-α,α,β,β-d4)(cis/trans)
Glimepiride-d₄(phenylethyl-α,α,β,β-d₄)(cis/trans) is the deuterium labeled .

HY-W020044S

*DL-alpha-Tocopherol-13C3*
DL-alpha-Tocopherol- ¹³C₃ is the ¹³C-labeled DL-alpha-Tocopherol. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .

HY-W145656S

α,β-Trehalose-d2
α,β-Trehalose-d₂ is the deuterium labeled α,β-Trehalose .

HY-115433S

α-Muricholic acid-d5
α-Muricholic acid-d₅ is the deuterium labeled α-Muricholic acid. α-Muricholic acid is the most abundant primary bile acid in rodents .

HY-115433S1

α-Muricholic acid-d4
α-Muricholic acid-d₄ is the deuterium labeled α-Muricholic acid. α-Muricholic acid is the most abundant primary bile acid in rodents .

HY-N5142S

α-Terpineol-d3
α-Terpineol-d₃ is the deuterium labeled α-Terpineol . α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria ^[2].α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption .

HY-146787S

7α,24(R/S)-Dihydroxycholestenone-d7
7α,24(R/S)-Dihydroxycholestenone-d₇ is deuterium labeled 7α,24(R/S)-Dihydroxycholestenone.

HY-146784S

7α,24(R/S)-Dihydroxycholesterol-d7
7α,24(R/S)-Dihydroxycholesterol-d₇ is deuterium labeled 7α,24(R/S)-Dihydroxycholesterol.

HY-150718S

α-Ketoisohexanoic acid-d3 sodium
α-Ketoisohexanoic acid-d₃ (sodium) is the deuterium labeled α-Ketoisohexanoic acid sodium .

HY-W017406S

L-α-Phenyl-glycine-d5
L-α-Phenyl-glycine-d₅ is the deuterium labeled L-α-Phenyl-glycine.

HY-W010249S

D-α-Phenyl-glycine-d5
D-α-Phenyl-glycine-d₅ is the deuterium labeled D-α-Phenyl-glycine.

HY-N8847S

α-Ionone-13C3
α-Ionone- ¹³C₃ is the ¹³C labeled α-Ionone .

HY-N0728S

α-Linolenic acid-d5
α-Linolenic acid-d₅ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-N0728S2

α-Linolenic acid-d14
α-Linolenic acid-d₁₄ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-144241S

*DL-Alpha-tocopherol nicotinate-d9*
DL-Alpha-tocopherol nicotinate-d₉ is the deuterium labeled DL-Alpha-tocopherol nicotinate .

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