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  5. AKR1C1 Antibody (YA7189)

AKR1C1 Antibody (YA7189)

Cat. No.: HY-P87505
User Guide for Antibodies Technical Support

AKR1C1 Antibody (YA7189) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to AKR1C1.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

AKR1C1 Antibody (YA7189) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to AKR1C1.
Background

AKR1C1 is a cytosolic aldo-keto reductase that catalyzes the NADH- and NADPH-dependent reduction of ketosteroids to hydroxysteroids (by similar). It primarily functions as a reductase in vivo with broad positional specificity for steroid positions 3, 17, and 20, regulating the metabolism of hormones including estrogens and androgens (by similar). The enzyme can also reduce conjugated steroids like 5alpha-dihydrotestosterone sulfate and exhibits affinity for bile acids.
Gene ID
SwissProt ID
Synonyms
C9; DD1; DDH; DDH1; H-37; HBAB; MBAB; HAKRC; DD1/DD2; 2-ALPHA-HSD; 20-ALPHA-HSD
Molecular Weight

Predicted band size: 37 kDa; Observed band size: 37 kDa
Purity

affinity purified.
Modification

Unmodified
Product Categories

Primary Antibody; Mouse Monoclonal Antibody
Clonality

Monoclonal
Host

Mouse
Predicted Reactivity

Human, Mouse

Note: The predicted reactivity is for reference only, not as a product performance guarantee.
Dilution Ratio

WB: 1:1,000-1:2,000; IHC-P: 1:50-1:200
Application

WB, IHC-P
Positive Control

HepG2 cell lysate, U-87 MG cell lysate, HeLa cell lysate, A431 cell lysate
Appearance

Liquid
Formulation

Supplied in PBS with 0.05% sodium azide
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG2a
Immunogen

Recombinant protein within Human AKR1C1 aa 180-323 / 323.
Documentation
User Guide for Antibodies (1077 KB)

AKR1C1 Antibody (YA7189) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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AKR1C1 Antibody (YA7189)
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