2. NF-κB MAPK/ERK Pathway Stem Cell/Wnt
  3. NF-κB p38 MAPK ERK JNK
  4. Anti-inflammatory agent 100

Anti-inflammatory agent 100 (Compound (+)-4S-23) is an anti-inflammatory agent. Anti-inflammatory agent 100 inhibits MAPK and NF-κB signaling, and also inhibits NF-κB pathway by suppressing the phosphorylation of IκB-α and blocking nuclear translocation of phosphorylated p65. Anti-inflammatory agent 100 inhibits NO production (IC50: 0.5 μM) and TNF-α, IL-6, IL-1β secretion.

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Anti-inflammatory agent 100 Chemical Structure

Anti-inflammatory agent 100 Chemical Structure

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Anti-inflammatory agent 100 Related Antibodies

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Description

Anti-inflammatory agent 100 (Compound (+)-4S-23) is an anti-inflammatory agent. Anti-inflammatory agent 100 inhibits MAPK and NF-κB signaling, and also inhibits NF-κB pathway by suppressing the phosphorylation of IκB-α and blocking nuclear translocation of phosphorylated p65. Anti-inflammatory agent 100 inhibits NO production (IC50: 0.5 μM) and TNF-α, IL-6, IL-1β secretion[1].

Molecular Weight

389.40

Formula

C22H19N3O4
SMILES

O=C1N2C(C(N(C)C([C@@H]2CC3=CC=CC=C3OCC=C)=O)=O)=NC4=CC=CC=C41
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Anti-inflammatory agent 100 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-inflammatory agent 100NF-κBp38 MAPKERKJNKNuclear factor-κBNuclear factor-kappaBExtracellular signal regulated kinasesc-Jun N-terminal kinaseAnti-inflammatoryMAPK signalingphosphorylated p65Inhibitorinhibitorinhibit

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