2. Others NF-κB PI3K/Akt/mTOR Apoptosis
  3. Reference Standards Keap1-Nrf2 Akt ASK1 Apoptosis
  4. Aceglutamide (Standard)

Aceglutamide (Standard)  (Synonyms: α-N-Acetyl-L-glutamine (Standard); N2-Acetylglutamine (Standard))

Cat. No.: HY-B1065R Purity: ≥98%
Handling Instructions Technical Support

Aceglutamide (α-N-Acetyl-L-glutamine; N2-Acetylglutamine) (Standard) is the analytical standard of Aceglutamide (HY-B1065). This product is intended for research and analytical applications. Aceglutamide (α-N-Acetyl-L-glutamine; N2-Acetylglutamine) is a neuroprotectant that can penetrate the blood-brain barrier. Aceglutamide can enhance the antioxidant systems of glutathione (GSH), thioredoxin (Trx) and Nrf2. Aceglutamide also inhibits ASK1 and TRAF1, activates the Akt/Bcl-2 anti-apoptotic pathway, enhances the activity of antioxidant enzymes and reduces oxidative damage. Aceglutamide can improve neurological deficits after cerebral ischemia, reduce infarct volume, and inhibit neuronal apoptosis, especially substantia nigra dopaminergic neurons. Aceglutamide can reduce cerebral ischemia/reperfusion injury, improve motor dysfunction, and is used in ischemic stroke-related research.

For research use only. We do not sell to patients.

Aceglutamide (Standard) Chemical Structure

Aceglutamide (Standard) Chemical Structure

CAS No. : 2490-97-3

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Description

Aceglutamide (α-N-Acetyl-L-glutamine; N2-Acetylglutamine) (Standard) is the analytical standard of Aceglutamide (HY-B1065). This product is intended for research and analytical applications. Aceglutamide (α-N-Acetyl-L-glutamine; N2-Acetylglutamine) is a neuroprotectant that can penetrate the blood-brain barrier. Aceglutamide can enhance the antioxidant systems of glutathione (GSH), thioredoxin (Trx) and Nrf2. Aceglutamide also inhibits ASK1 and TRAF1, activates the Akt/Bcl-2 anti-apoptotic pathway, enhances the activity of antioxidant enzymes and reduces oxidative damage. Aceglutamide can improve neurological deficits after cerebral ischemia, reduce infarct volume, and inhibit neuronal apoptosis, especially substantia nigra dopaminergic neurons. Aceglutamide can reduce cerebral ischemia/reperfusion injury, improve motor dysfunction, and is used in ischemic stroke-related research.

Molecular Weight

188.18

Formula

C7H12N2O4
CAS No.
SMILES

O=C(N)CC[C@@H](C(O)=O)NC(C)=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Aceglutamide (Standard) Related Classifications

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Keywords:

Aceglutamide (Standard)2490-97-3α-N-Acetyl-L-glutamine (Standard)N2-Acetylglutamine (Standard)Reference StandardsKeap1-Nrf2AktASK1ApoptosisPKBProtein kinase BApoptosis signal-regulating kinase 1MAP3K5MAPKKK5Mitogen-activated protein kinase kinase kinase 5MEK kinase 5Inhibitorinhibitorinhibit

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