2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. (S)-Padsevonil

(S)-Padsevonil is the S-enantiomer of Padsevonil (HY-109009).Padsevonil (UCB0942) is a potent antiepileptic agent that selectively acts on presynaptic and postsynaptic targets. Padsevonil binds to synaptic vesicular protein 2 (SV2) with high affinity. Padsevonil is also a positive allosteric modulator and partial agonist of GABAAR, with high potency against α1 and α5 receptors. Padsevonil has antiepileptic effects in a variety of rodent models.

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(S)-Padsevonil Chemical Structure

(S)-Padsevonil Chemical Structure

CAS No. : 1294001-37-8

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(S)-Padsevonil Related Antibodies

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Description

(S)-Padsevonil is the S-enantiomer of Padsevonil (HY-109009).Padsevonil (UCB0942) is a potent antiepileptic agent that selectively acts on presynaptic and postsynaptic targets. Padsevonil binds to synaptic vesicular protein 2 (SV2) with high affinity. Padsevonil is also a positive allosteric modulator and partial agonist of GABAAR, with high potency against α1 and α5 receptors. Padsevonil has antiepileptic effects in a variety of rodent models[1][2].

Molecular Weight

432.80

Formula

C14H14ClF5N4O2S
CAS No.
Appearance

Solid

SMILES

O=C1N(C[C@H](CC(F)(F)Cl)C1)CC(N(N=C(COC)S2)C2=N3)=C3C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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(S)-Padsevonil Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-Padsevonil1294001-37-8(S)-UCB-0942GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorPadsevonilCHONeuronsEpilepsy modelInhibitorinhibitorinhibit

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