CACNA1F Antibody (YA5947)

CACNA1F Antibody (YA5947) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CACNA1F. It can be applicated for WB, FC assays, in the background of human.

CACNA1F encodes a voltage-sensitive calcium channel (VSCC) that mediates calcium ion entry into excitable cells and participates in various calcium-dependent processes, including muscle contraction, hormone/neurotransmitter release, gene expression, cell motility, division, and death. The alpha-1F isoform generates L-type calcium currents, classified as 'high-voltage activated' (HVA), and is blocked by dihydropyridines (DHP), phenylalkylamines, and benzothiazepines. It activates at more negative voltages and lacks calcium-dependent inactivation (CDI) during depolarization despite calcium influx. By similar function: Voltage-dependent L-type calcium channels activate at more hyperpolarized voltages and exhibit robust CDI during depolarizations due to calcium ion influx.

O60840

Observed band size: 217 kDa

Protein A

Non-conjugated

Unmodified

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Monoclonal

Rabbit

Human

WB: 1:1000-5000; FC 1:100-300

WB, FC

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG