2. Immunology/Inflammation
  3. Interleukin Related COX
  4. Vasoactive intestinal peptide

Vasoactive intestinal peptide is an agonist of VPAC1/VPAC2 receptor (G-protein-coupled receptors). Vasoactive intestinal peptide reduces corneal perforation rate, bacterial load, and excessive neutrophil infiltration in Pseudomonas aeruginosa-induced keratitis models. Vasoactive intestinal peptide enhances anti-inflammatory mediators like IL-10 and TGF-β, inhibites pro-inflammatory factors such as IL-1β and TNF-α, and upregulates lipid mediator-related enzymes (SOCS3, COX-2, ALOX12) to promote inflammation resolution. Vasoactive intestinal peptide is promising for research of ocular infectious diseases.

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Vasoactive intestinal peptide Chemical Structure

Vasoactive intestinal peptide Chemical Structure

CAS No. : 37221-79-7

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Vasoactive intestinal peptide Related Antibodies

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Description

Vasoactive intestinal peptide is an agonist of VPAC1/VPAC2 receptor (G-protein-coupled receptors). Vasoactive intestinal peptide reduces corneal perforation rate, bacterial load, and excessive neutrophil infiltration in Pseudomonas aeruginosa-induced keratitis models. Vasoactive intestinal peptide enhances anti-inflammatory mediators like IL-10 and TGF-β, inhibites pro-inflammatory factors such as IL-1β and TNF-α, and upregulates lipid mediator-related enzymes (SOCS3, COX-2, ALOX12) to promote inflammation resolution. Vasoactive intestinal peptide is promising for research of ocular infectious diseases[1].

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COX-2

 

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[Vasoactive intestinal peptide]
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Vasoactive intestinal peptide Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vasoactive intestinal peptide37221-79-7Interleukin RelatedCOXILCyclooxygenaseVPAC1VPAC2 receptorkeratitisocular infectious diseasesInhibitorinhibitorinhibit

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