2. PI3K/Akt/mTOR Apoptosis
  3. PI3K mTOR Apoptosis
  4. PWT-33597 free base

PWT-33597 free base  (Synonyms: VDC-597 free base)

Cat. No.: HY-15960
Handling Instructions Technical Support

PWT-33597 (VDC-597) free base is a dual inhibitor of PI3Kα and mTOR, which can effectively block the signaling downstream of PI3K and mTOR. PWT-33597 free base is capable of inducing tumor cell apoptosis and inhibiting tumor growth. PWT-33597 free base has anti-tumor activity and can be used in the research of tumors such as renal cell carcinoma.

For research use only. We do not sell to patients.

PWT-33597 free base Chemical Structure

PWT-33597 free base Chemical Structure

CAS No. : 1246203-32-6

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Other Forms of PWT-33597 free base:

PWT-33597 free base Related Antibodies

Top Publications Citing Use of Products

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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mTOR mTORC1 mTORC2

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Description

PWT-33597 (VDC-597) free base is a dual inhibitor of PI3Kα and mTOR, which can effectively block the signaling downstream of PI3K and mTOR. PWT-33597 free base is capable of inducing tumor cell apoptosis and inhibiting tumor growth. PWT-33597 free base has anti-tumor activity and can be used in the research of tumors such as renal cell carcinoma[1].

Molecular Weight

588.63

Formula

C26H30F2N8O4S
CAS No.
SMILES

CN(CCS(=O)(NC1=CC=C(C2=NC(N3C4=CC=CC(OC)=C4N=C3C(F)F)=NC(N5CCOCC5)=N2)C=C1)=O)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PWT-33597 free base Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PWT-335971246203-32-6VDC-597PWT33597PWT 33597VDC597VDC 597PI3KmTORApoptosisPhosphoinositide 3-kinaseMammalian target of RapamycinRCC786-0 cellsInhibitorinhibitorinhibit

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