2. PI3K/Akt/mTOR Apoptosis
  3. PI3K Apoptosis
  4. Buparlisib Hydrochloride (Standard)

Buparlisib Hydrochloride (Standard) 

Cat. No.: HY-15180R Purity: ≥98%
Handling Instructions Technical Support

Buparlisib (Hydrochloride) (Standard) is the analytical standard of Buparlisib (Hydrochloride). This product is intended for research and analytical applications. Buparlisib Hydrochloride (BKM120 Hydrochloride) is a pan-class I PI3K inhibitor, with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively.

For research use only. We do not sell to patients.

Buparlisib Hydrochloride (Standard) Chemical Structure

Buparlisib Hydrochloride (Standard) Chemical Structure

CAS No. : 1312445-63-8

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Description

Buparlisib (Hydrochloride) (Standard) is the analytical standard of Buparlisib (Hydrochloride). This product is intended for research and analytical applications. Buparlisib Hydrochloride (BKM120 Hydrochloride) is a pan-class I PI3K inhibitor, with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively.

Molecular Weight

446.85

Formula

C18H22ClF3N6O2
CAS No.
SMILES

NC(N=C1)=CC(C(F)(F)F)=C1C2=NC(N3CCOCC3)=NC(N4CCOCC4)=C2.[H]Cl
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Buparlisib Hydrochloride (Standard) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Buparlisib Hydrochloride (Standard)1312445-63-8PI3KApoptosisPhosphoinositide 3-kinaseInhibitorinhibitorinhibit

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