1. Antibodies
  2. Primary Antibodies
  3. Monoclonal Antibodies
  4. PDHA1 Antibody (YA5141)

PDHA1 Antibody (YA5141)

Cat. No.: HY-P85449
User Guide for Antibodies Technical Support

PDHA1 Antibody (YA5141) is a mouse-derived and non-conjugated monoclonal antibody, targeting to PDHA1. It can be applicated for WB, ICC/IF assays, in the background of human, mouse, rat, bovine, dog, pig.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

PDHA1 Antibody (YA5141) is a mouse-derived and non-conjugated monoclonal antibody, targeting to PDHA1. It can be applicated for WB, ICC/IF assays, in the background of human, mouse, rat, bovine, dog, pig.

Background

PDHA1 protein, a crucial constituent of the pyruvate dehydrogenase complex, plays a pivotal role in orchestrating the comprehensive conversion of pyruvate into acetyl-CoA and CO2. This enzymatic process establishes a fundamental link between the glycolytic pathway and the tricarboxylic acid (TCA) cycle, facilitating the seamless integration of metabolic pathways. PDHA1's catalytic function is essential for the efficient transformation of pyruvate, ensuring the flow of carbon substrates into the TCA cycle for subsequent energy generation and metabolic homeostasis within the cell.

Gene ID
SwissProt ID
Synonyms
PDHA1; PHE1A; Pyruvate dehydrogenase E1 component subunit alpha; somatic form, mitochondrial; PDHE1-A type I
Molecular Weight

Predicted band size: 43 kDa;

Purity

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human, Mouse, Rat, Bovine, Dog, Pig

Dilution Ratio

WB: 1:1000-1:2000; ICC/IF: 1:100-1:500

Application

WB, ICC/IF

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Immunogen

Purified recombinant human PDH-E1α (C-terminus) protein fragments expressed in E.coli.

Documentation

PDHA1 Antibody (YA5141) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PDHA1 Antibody (YA5141)
Cat. No.:
HY-P85449
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