2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species HIF/HIF Prolyl-Hydroxylase
  4. Terpestacin

Terpestacin is found in Phoma exigua var. heteromorpha. Terpestacin binds to UQCRB to inhibit the production of mitochondrial ROS and HIF-1α. Terpestacin inhibits tumor angiogenesis in the FM3A breast cancer cell xenograft mouse model. Terpestacin has antitumor activity and phytotoxicity.

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Terpestacin Chemical Structure

Terpestacin Chemical Structure

CAS No. : 146436-22-8

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Terpestacin Related Antibodies

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Description

Terpestacin is found in Phoma exigua var. heteromorpha. Terpestacin binds to UQCRB to inhibit the production of mitochondrial ROS and HIF-1α. Terpestacin inhibits tumor angiogenesis in the FM3A breast cancer cell xenograft mouse model. Terpestacin has antitumor activity and phytotoxicity[1][2].

Molecular Weight

402.57

Formula

C25H38O4
CAS No.
SMILES

OC[C@@H](C)C1=C(C([C@@]2([C@@]1(C/C=C([C@H](CC/C(C)=C/CC/C(C)=C/C2)O)\C)[H])C)=O)O
Structure Classification
Initial Source

Phoma exigua var. heteromorpha
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Terpestacin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Terpestacin146436-22-8Reactive Oxygen SpeciesHIF/HIF Prolyl-HydroxylaseHypoxia-inducible factorsHIFsHIF-PHAntitumor activityphytotoxicitycytochalasinsFM3APhoma exigua var. heteromorphaInhibitorinhibitorinhibit

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