HP1 alpha Antibody (YA4033)

Cat. No.: HY-P84336: Data Sheet User Guide for Antibodies
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HP1 alpha Antibody (YA4033) is a mouse-derived and non-conjugated IgG1 antibody, targeting to CBX5. It can be applicated for WB, IHC-P, ICC/IF, ELISA assays, in the background of human, mouse.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
Properties
Documentation

Description	HP1 alpha Antibody (YA4033) is a mouse-derived and non-conjugated IgG1 antibody, targeting to CBX5. It can be applicated for WB, IHC-P, ICC/IF, ELISA assays, in the background of human, mouse.
Background	CBX5 is a component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. However, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). CBX5 may contribute to the association of heterochromatin with the inner nuclear membrane through interactions with the lamin-B receptor (LBR). Additionally, it is involved in the formation of kinetochores via interaction with the MIS12 complex subunit NSL1 and is required for the formation of the inner centromere.
Gene ID	23468 [NCBI]
SwissProt ID	P45973
Synonyms	HP1; HP1A; HEL25
Molecular Weight	Predicted band size: 22 kDa; Observed band size: 26 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human, Mouse
Dilution Ratio	WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; ELISA: 1/10000
Application	WB, IHC-P, ICC/IF, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG1
Immunogen	Purified recombinant fragment of human CBX5 (AA: 1-191) expressed in E. Coli.
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

HP1 alpha Antibody (YA4033) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HP1 alpha Antibody (YA4033)

Biological Activity

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HP1 alpha Antibody (YA4033) Related Classifications

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