H2-D1 Protein, Mouse (His-SUMO)

The H2-D1 protein is a key element of the immune system and is actively involved in the presentation of foreign antigens. As a major histocompatibility complex class I (MHC-I) component, H2-D1 forms a heterodimer with α and β chains and is essential for recognizing and presenting antigen to cytotoxic T cells. H2-D1 Protein, Mouse (His-SUMO) is the recombinant mouse-derived H2-D1 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

The H2-D1 Protein plays a crucial role in the immune system by participating in the presentation of foreign antigens. As a key component of the major histocompatibility complex class I (MHC-I), H2-D1 forms a heterodimer with an alpha chain and a beta chain (beta-2-microglobulin). This complex is essential for the recognition and presentation of antigens to cytotoxic T cells, contributing to the surveillance and defense mechanisms of the immune system. Through its involvement in antigen presentation, H2-D1 plays a vital role in the orchestration of immune responses, facilitating the identification and elimination of foreign entities by the adaptive immune system.

Mouse

E. coli

N-His;N-SUMO

P01900 (G25-T311)

14964

Extracellular Domain

GSHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARWIEQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQSAGGSHTLQWMAGCDVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQAGAAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTLRCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPLGKEQKYTCHVEHEGLPEPLTLRWGKEEPPSSTKTNT

Approximately 50-54 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.22 μm filtered solution of 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.