1. Vitamin D Related/Nuclear Receptor PROTAC
  2. Estrogen Receptor/ERR Target Protein Ligand-Linker Conjugates
  3. AZD9496-O-C3-O-C3-O-C-acid

AZD9496-O-C3-O-C3-O-C-acid is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for ERα (HY-12870) and a PROTAC linker, which recruits E3 ligases. AZD9496-O-C3-O-C3-O-C-acid can be used for synthesis of PROTAC AZ'6421 (HY-135312).

For research use only. We do not sell to patients.

AZD9496-O-C3-O-C3-O-C-acid

AZD9496-O-C3-O-C3-O-C-acid Chemical Structure

CAS No. : 2361117-48-6

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Description

AZD9496-O-C3-O-C3-O-C-acid is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for ERα (HY-12870) and a PROTAC linker, which recruits E3 ligases. AZD9496-O-C3-O-C3-O-C-acid can be used for synthesis of PROTAC AZ'6421 (HY-135312)[1].

IC50 & Target[1]

ERα

 

Molecular Weight

562.62

Formula

C30H37F3N2O5

CAS No.
SMILES

CC(C)(F)CN1[C@H](C2=C(C=C(C=C2F)OCCCOCCCOCC(O)=O)F)C3=C(C[C@H]1C)C4=CC=CC=C4N3

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
AZD9496-O-C3-O-C3-O-C-acid
Cat. No.:
HY-176364
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