2. Neuronal Signaling
  3. OGT
  4. UDP-GlcNAc disodium

UDP-GlcNAc disodium  (Synonyms: UDP-α-D-N-Acetylglucosamine disodium)

Cat. No.: HY-112174 Purity: 99.92%
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UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (OGT).

For research use only. We do not sell to patients.

UDP-GlcNAc disodium Chemical Structure

UDP-GlcNAc disodium Chemical Structure

CAS No. : 91183-98-1

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Based on 5 publication(s) in Google Scholar

Other Forms of UDP-GlcNAc disodium:

UDP-GlcNAc disodium Related Antibodies

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  • Purity & Documentation

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Description

UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (OGT).

In Vitro

OGT is a nucleocytoplasmic glycosyltransferase (uridine diphospho-N--acetylglucosamine:polypeptide β-N-acetylglucosaminyltransferase or O-GlcNAc transferase) assigned to the GT41 family in the CAZY (Carbohydrate-Active enZYme) database. Using UDP-GlcNAc Disodium Salt (UDP-GlcNAc) as the donor substrate, this enzyme modifies thousands of proteins by adding a unique N-acetylglucosamine residue onto acceptor substrates mainly confined within cytosol and nucleus[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

UDP-GlcNAc disodium Related Antibodies
Molecular Weight

651.32

Formula

C17H25N3Na2O17P2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@H](N2C(NC(C=C2)=O)=O)O[C@H](COP(OP(O[C@@H]3[C@@H]([C@H]([C@H](O)[C@@H](CO)O3)O)NC(C)=O)(O[Na])=O)(O[Na])=O)[C@H]1O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (191.92 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5353 mL 7.6767 mL 15.3534 mL
5 mM 0.3071 mL 1.5353 mL 3.0707 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.92%

SDS (393 KB)

COA (252 KB) HNMR (290 KB) CNMR (442 KB) RP-HPLC (236 KB) MS (68 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.5353 mL 7.6767 mL 15.3534 mL 38.3836 mL
5 mM 0.3071 mL 1.5353 mL 3.0707 mL 7.6767 mL
10 mM 0.1535 mL 0.7677 mL 1.5353 mL 3.8384 mL
15 mM 0.1024 mL 0.5118 mL 1.0236 mL 2.5589 mL
20 mM 0.0768 mL 0.3838 mL 0.7677 mL 1.9192 mL
25 mM 0.0614 mL 0.3071 mL 0.6141 mL 1.5353 mL
30 mM 0.0512 mL 0.2559 mL 0.5118 mL 1.2795 mL
40 mM 0.0384 mL 0.1919 mL 0.3838 mL 0.9596 mL
50 mM 0.0307 mL 0.1535 mL 0.3071 mL 0.7677 mL
60 mM 0.0256 mL 0.1279 mL 0.2559 mL 0.6397 mL
80 mM 0.0192 mL 0.0960 mL 0.1919 mL 0.4798 mL
100 mM 0.0154 mL 0.0768 mL 0.1535 mL 0.3838 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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UDP-GlcNAc disodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UDP-GlcNAc disodium91183-98-1UDP-α-D-N-Acetylglucosamine disodiumOGTO-linked N-acetylglucosaminyltransferaseO-GlcNAc transferaseInhibitorinhibitorinhibit

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