Pyruvate Dehydrogenase E1 alpha Antibody (YA5196)

Pyruvate Dehydrogenase E1 alpha Antibody (YA5196) is a mouse-derived and non-conjugated monoclonal antibody, targeting to PDHA1. It can be applicated for WB, ICC assays, in the background of human, mouse.

PDHA1 protein, a crucial constituent of the pyruvate dehydrogenase complex, plays a pivotal role in orchestrating the comprehensive conversion of pyruvate into acetyl-CoA and CO2. This enzymatic process establishes a fundamental link between the glycolytic pathway and the tricarboxylic acid (TCA) cycle, facilitating the seamless integration of metabolic pathways. PDHA1's catalytic function is essential for the efficient transformation of pyruvate, ensuring the flow of carbon substrates into the TCA cycle for subsequent energy generation and metabolic homeostasis within the cell.

P08559

Observed band size: 43 kDa

affinity chromatography.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse

WB: 1:1000; ICC: 1:100

WB, ICC

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Purified recombinant human Pyruvate Dehydrogenase protein fragments expressed in E.coli.