2. Stem Cell/Wnt PI3K/Akt/mTOR Apoptosis
  3. GSK-3 Apoptosis
  4. SB 415286 (Standard)

SB 415286 (Standard) is the analytical standard of SB 415286. This product is intended for research and analytical applications. SB 415286 is a potent and selective cell permeable inhibitor of GSK-3α, with an IC50 of 77.5 nM, and a Ki of 30.75 nM; SB 415286 is equally effective at inhibiting human GSK-3α and GSK-3β.

For research use only. We do not sell to patients.

SB 415286 (Standard) Chemical Structure

SB 415286 (Standard) Chemical Structure

CAS No. : 264218-23-7

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Description
Molecular Weight

359.72

Formula

C16H10ClN3O5
CAS No.
SMILES

O=C(C(NC1=CC=C(O)C(Cl)=C1)=C2C3=CC=CC=C3[N+]([O-])=O)NC2=O
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SB 415286 (Standard) Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SB 415286 (Standard)264218-23-7GSK-3ApoptosisGlycogen synthase kinase-3Glycogen synthase kinase 3Inhibitorinhibitorinhibit

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