2. Vitamin D Related/Nuclear Receptor PROTAC
  3. Estrogen Receptor/ERR Ligands for Target Protein for PROTAC
  4. ER ligand-11

ER ligand-11 is the ligand for ERα and can be used for synthesis of PROTACs, such as PROTAC ERα Degrader-12 (HY-174453).

For research use only. We do not sell to patients.

ER ligand-11 Chemical Structure

ER ligand-11 Chemical Structure

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ER ligand-11 Related Antibodies

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

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Description

ER ligand-11 is the ligand for ERα and can be used for synthesis of PROTACs, such as PROTAC ERα Degrader-12 (HY-174453)[1].

In Vitro

ER ligand-11 exhibits IC50 of 0.39, 13.72, 2.2, 3.33, 2.16 and 2.11 μM for MCF-7, MCF-10A, MCF-7D538G, MCF-7Y537S, MCF-7EGFR, and LCC-2 cell lines[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ER ligand-11 Related Antibodies
Molecular Weight

375.63

Formula

C24H45N3
SMILES

NCC1=C(C(CN)=C(C(CN)=C1CCCCC)CCCCC)CCCCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ER ligand-11 Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ER ligand-11ER ligand11ER ligand 11Estrogen Receptor/ERRLigands for Target Protein for PROTACTarget Protein-binding MoietyBreast cancerERαPROTACInhibitorinhibitorinhibit

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ER ligand-11
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HY-174475
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