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  4. GLRA3 Protein, Human (sf9, Strep)

GLRA3 Protein, Human (sf9, Strep) is the recombinant human-derived GLRA3, expressed by sf9 insect cells , with Strep labeled tag. ,

For research use only. We do not sell to patients.

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Description

GLRA3 Protein, Human (sf9, Strep) is the recombinant human-derived GLRA3, expressed by sf9 insect cells , with Strep labeled tag. ,
Background

GLRA3 is a subtype of glycine receptors, which are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine, and its characteristics depend on subunit composition, with heteropentameric channels displaying faster closure (By similarity). It plays a key role in down-regulating neuronal excitability (By similarity), contributes to inhibitory postsynaptic currents (By similarity), enhances pain perception in response to elevated prostaglandin E2 levels (By similarity), and is involved in cellular responses to ethanol (By similarity).
Species

Human
Source

Sf9 insect cells
Tag

Strep
Accession

O75311-1 (M1–H460, del 343–418)
Gene ID

8001
Protein Length

Full Length of Isoform-1 Mature Protein
Synonyms
Glycine receptor subunit alpha-3; GLRA3; Homo sapiens; Human; Chloride channel; Ion channel; Ligand-gated ion channel; Receptor
Predicted Molecular Mass
45.6 kDa
Glycosylation
Yes
Purity

Greater than 95% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

GLRA3 Protein, Human (sf9, Strep) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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GLRA3 Protein, Human (sf9, Strep)
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