2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. L-745870 (Standard)

L-745870 (Standard) is the analytical standard of L-745870. This product is intended for research and analytical applications. L-745870 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors.

For research use only. We do not sell to patients.

L-745870 (Standard) Chemical Structure

L-745870 (Standard) Chemical Structure

CAS No. : 158985-00-3

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L-745870 (Standard) Related Classifications

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Keywords:

L-745870 (Standard)158985-00-3Dopamine ReceptorHumandopamineD4receptorbrainpenetrationneurolepticsInhibitorinhibitorinhibit

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