2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK Immunology/Inflammation Apoptosis
  3. EGFR IFNAR Interleukin Related TNF Receptor Complement System Apoptosis
  4. Eps8 peptide 327

Eps8 peptide 327 is an HLA-A*2402-restricted peptide antigen derived from Eps8 protein. Eps8 peptide 327 has potent antitumor activity with significant cytotoxicity. Eps8 peptide 327 effectively inhibits cancer cells proliferation, induces apoptosis and disrupts EGFR signal pathway by inhibiting downstream signals (such as IL-2, TNF-α and IFN-γ) expression and the Eps8/EGFR interaction. Eps8 peptide 327 significantly inhibits tumor growth in HT-29 xenograft mcie models.

For research use only. We do not sell to patients.

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Eps8 peptide 327 Chemical Structure

Eps8 peptide 327 Chemical Structure

CAS No. : 1988684-26-9

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Eps8 peptide 327 Related Antibodies

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Description

Eps8 peptide 327 is an HLA-A*2402-restricted peptide antigen derived from Eps8 protein. Eps8 peptide 327 has potent antitumor activity with significant cytotoxicity. Eps8 peptide 327 effectively inhibits cancer cells proliferation, induces apoptosis and disrupts EGFR signal pathway by inhibiting downstream signals (such as IL-2, TNF-α and IFN-γ) expression and the Eps8/EGFR interaction. Eps8 peptide 327 significantly inhibits tumor growth in HT-29 xenograft mcie models[1].

IC50 & Target[1]

IL-2

 

Molecular Weight

1176.34

Formula

C56H77N11O15S
CAS No.
Sequence

Glu-Phe-Leu-Asp-Cys-Phe-Gln-Lys-Phe
Sequence Shortening

EFLDCFQKF
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Eps8 peptide 327 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eps8 peptide 3271988684-26-9Eps8(327-335)EGFRIFNARInterleukin RelatedTNF ReceptorComplement SystemApoptosisEpidermal growth factor receptorErbB-1HER1Interferon-α/β receptorInterferon-alpha/beta receptor ILTumor Necrosis Factor ReceptorTNFRHLA-A*2402Restricted peptide antigenEps8AntitumorA549 cellsColo320 cellsHepG2 cellsHT-29 cellsHT-29 xenograft mcie modelsInhibitorinhibitorinhibit

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