1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 3,7,11,15-Tetramethyl-2-hexadecen-1-ol

3,7,11,15-Tetramethyl-2-hexadecen-1-ol 

Cat. No.: HY-W107616 Purity: 97.69%
Handling Instructions Technical Support

3,7,11,15-Tetramethyl-2-hexadecen-1-ol can be used to synthesize vitamin E and vitamin E's precursor vitamin K1. 3,7,11,15-Tetramethyl-2-hexadecen-1-ol regulates transcription in cells through the transcription factor PPAR-alpha and the retinoid X receptor (RXR)43.

For research use only. We do not sell to patients.

3,7,11,15-Tetramethyl-2-hexadecen-1-ol Chemical Structure

3,7,11,15-Tetramethyl-2-hexadecen-1-ol Chemical Structure

CAS No. : 7541-49-3

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Other Forms of 3,7,11,15-Tetramethyl-2-hexadecen-1-ol:

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  • Biological Activity

  • Purity & Documentation

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Description

3,7,11,15-Tetramethyl-2-hexadecen-1-ol can be used to synthesize vitamin E and vitamin E's precursor vitamin K1. 3,7,11,15-Tetramethyl-2-hexadecen-1-ol regulates transcription in cells through the transcription factor PPAR-alpha and the retinoid X receptor (RXR)43[1].

IC50 & Target

Human Endogenous Metabolite

 

Cellular Effect
Cell Line Type Value Description References
HepG2 IC50
> 100 μM
Compound: 14
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by neutral red assay
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by neutral red assay
[PMID: 28318944]
KB IC50
> 100 μM
Compound: 14
Cytotoxicity against human KB cells assessed as growth inhibition after 72 hrs by neutral red assay
Cytotoxicity against human KB cells assessed as growth inhibition after 72 hrs by neutral red assay
[PMID: 28318944]
Lu1 IC50
> 100 μM
Compound: 14
Cytotoxicity against human Lu1 cells assessed as growth inhibition after 72 hrs by neutral red assay
Cytotoxicity against human Lu1 cells assessed as growth inhibition after 72 hrs by neutral red assay
[PMID: 28318944]
MCF7 IC50
> 100 μM
Compound: 14
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by neutral red assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by neutral red assay
[PMID: 28318944]
Molecular Weight

296.54

Formula

C20H40O

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

OCC=C(CCCC(CCCC(CCCC(C)C)C)C)C

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (337.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3722 mL 16.8611 mL 33.7223 mL
5 mM 0.6744 mL 3.3722 mL 6.7445 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 97.69%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3722 mL 16.8611 mL 33.7223 mL 84.3057 mL
5 mM 0.6744 mL 3.3722 mL 6.7445 mL 16.8611 mL
10 mM 0.3372 mL 1.6861 mL 3.3722 mL 8.4306 mL
15 mM 0.2248 mL 1.1241 mL 2.2482 mL 5.6204 mL
20 mM 0.1686 mL 0.8431 mL 1.6861 mL 4.2153 mL
25 mM 0.1349 mL 0.6744 mL 1.3489 mL 3.3722 mL
30 mM 0.1124 mL 0.5620 mL 1.1241 mL 2.8102 mL
40 mM 0.0843 mL 0.4215 mL 0.8431 mL 2.1076 mL
50 mM 0.0674 mL 0.3372 mL 0.6744 mL 1.6861 mL
60 mM 0.0562 mL 0.2810 mL 0.5620 mL 1.4051 mL
80 mM 0.0422 mL 0.2108 mL 0.4215 mL 1.0538 mL
100 mM 0.0337 mL 0.1686 mL 0.3372 mL 0.8431 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
3,7,11,15-Tetramethyl-2-hexadecen-1-ol
Cat. No.:
HY-W107616
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