2. Metabolic Enzyme/Protease
  3. Glycosidase
  4. CTL26

CTL26 is a potent and orally active α-glucosidase inhibitor with an IC50 value of 2.81 µM. CTL26 shows anti-diabetic efficacy.

For research use only. We do not sell to patients.

CTL26

CTL26 Chemical Structure

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CTL26 Related Antibodies

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Description

CTL26 is a potent and orally active α-glucosidase inhibitor with an IC50 value of 2.81 µM. CTL26 shows anti-diabetic efficacy[1].

IC50 & Target

IC50: 2.81 µM (α-glucosidase)[1]
In Vivo

CTL26 (25, 50 mg/kg; p.o.; daily for 4 weeks) shows anti-diabetic efficacy in streptozocin (HY-13753)-induced diabetes mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 10-15g, SPF C57/6 J male mice (STZ-induced diabetes)[1]
Dosage: 25, 50 mg/kg
Administration: P.o.; daily for 4 weeks
Result: Exhibited continuously decreasing fasting blood glucose (FBG) levels, decreased the serum total cholesterol (TC) and triglycerides (TG) levels.
Molecular Weight

482.51

Formula

C25H18N6O3S
SMILES

O=C(NNC(NC1=CC([N+]([O-])=O)=CC=C1)=S)C2=CC3=C(C(C4=CC=CC=C4)=N2)NC5=CC=CC=C53
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CTL26 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CTL26CTL 26CTL-26Glycosidaseanti-diabeticfasting blood glucosecholesteroltriglyceridesInhibitorinhibitorinhibit

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HY-162637
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