2. Oligonucleotides
  3. Nucleosides and their Analogs
  4. U

U

Uracil

U (447):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15910
    5-BrdU 59-14-3 99.96%
    5-BrdU (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA. 5-BrdU is commonly used in the detection of proliferating cells.
    5-BrdU
  • HY-B1449
    Uridine 58-96-8 99.98%
    Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, which are connected by a β-N1-glycosidic bond.
    Uridine
  • HY-W011793
    4-Thiouridine 13957-31-8 99.23%
    4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response.
    4-Thiouridine
  • HY-113061
    Pseudouridine 1445-07-4 99.88%
    Pseudouridine is an isomer of uridine and the most abundant modified nucleoside in non-coding RNA. It fine-tunes and stabilizes regional structures in rRNA and tRNA, maintaining their functions in mRNA decoding, ribosome assembly, processing, and translation. Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis and hold promise for research on myelodysplastic syndrome (MDS)-related leukemia..
    Pseudouridine
  • HY-15345
    Tetrahydrouridine dihydrate 99.86%
    Tetrahydrouridine dihydrate (THU dihydrate) is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine.
    Tetrahydrouridine dihydrate
  • HY-112582
    N1-Methylpseudouridine 13860-38-3 99.97%
    N1-methyl-pseudouridine (1-Methylpseudouridine), a methylpseudouridine, outperforms 5 mC and 5 mC/N1-methyl-pseudouridine in translation. N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density.
    N1-Methylpseudouridine
  • HY-15345A
    Tetrahydrouridine 18771-50-1 99.89%
    Tetrahydrouridine dihydrate is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine.
    Tetrahydrouridine
  • HY-W009444
    5-Methyluridine 1463-10-1 99.88%
    5-Methyluridine (m5U) is an RNA modified nucleotide generated by RNA methyltransferases (such as TrmA and RumA), which mainly targets specific uracil sites in RNA molecules such as the T arm of tRNA and rRNA. 5-Methyluridine relies on enzyme recognition of RNA secondary/tertiary structures (such as the T loop of tRNA or the specific stem-loop structure of rRNA) and participates in physiological processes such as translation accuracy and ribosome function by stabilizing RNA folding or regulating base pairing.
    5-Methyluridine
  • HY-W011824
    2′-O-Methyluridine 2140-76-3 99.81%
    2'-O-methyluridine is found in rRNA, snRNA, snoRNA and tRNA of Archaea, Bacteria, and Eukaryota.
    2′-O-Methyluridine
  • HY-W009163
    5-Bromouridine 957-75-5 99.89%
    5-Bromouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
    5-Bromouridine
  • HY-W342664
    2'-Deoxy-2'-fluoro-5-iodouridine 55612-21-0 99.46%
    2'-Deoxy-2'-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
    2'-Deoxy-2'-fluoro-5-iodouridine
  • HY-151817
    5-Azidomethyl-uridine 24751-67-5 99.99%
    5-Azidomethyl-uridine is a click chemistry reagent containing an azide group.The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction. 5-Azidomethyl-uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    5-Azidomethyl-uridine
  • HY-W008662
    2'-Deoxy-5'-O-DMT-2'-fluorouridine 146954-74-7 99.94%
    2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity.
    2'-Deoxy-5'-O-DMT-2'-fluorouridine
  • HY-101970
    Deoxypseudouridine 39967-60-7 98.25%
    Deoxypseudouridine is a nucleoside analog.
    Deoxypseudouridine
  • HY-W341499
    5-Formyl-2'-deoxyuridine 4494-26-2 99.64%
    5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein.
    5-Formyl-2'-deoxyuridine
  • HY-154253
    5-Azidomethyl-2'-deoxyuridine 59090-48-1 99.67%
    5-Azidomethyl-2'-deoxyuridine (5-AmdU) is a purine nucleoside analog. 5-Azidomethyl-2'-deoxyuridine demonstrates effective radiosensitization in EMT6 tumor cells.. 5-Azidomethyl-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    5-Azidomethyl-2'-deoxyuridine
  • HY-111639
    2’-O,4’-C-Methyleneuridine 200435-92-3 99.57%
    2’-O,4’-C-Methyleneuridine (Compound 15a) is a bicyclic nucleoside.
    2’-O,4’-C-Methyleneuridine
  • HY-W393317
    5-Methoxycarbonylmethyl-2'-O-methyluridine 60197-31-1 99.80%
    5-Methoxycarbonylmethyl-2'-O-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis.
    5-Methoxycarbonylmethyl-2'-O-methyluridine
  • HY-W014306
    2',3'-Dideoxyuridine 5983-09-5 99.89%
    2',3'-Dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
    2',3'-Dideoxyuridine
  • HY-W251781
    4-Thio-2’-deoxyuridine 5580-20-1 ≥98.0%
    4-Thio-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
    4-Thio-2’-deoxyuridine