2. Apoptosis Immunology/Inflammation
  3. TNF Receptor Apoptosis NO Synthase
  4. VR11 aptamer

VR11 aptamer is a DNA-based TNF-α inhibitor with a KD of 7.0 nM. VR11 aptamer prevents TNFα-induced apoptosis and NO production. VR11 aptamer has non-immunogenicity and does not raise immune responses when injected intraperitoneally into C57BL/6 mice model. VR11 aptamer can be used for inflammatory diseases research.

For research use only. We do not sell to patients.

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VR11 aptamer

VR11 aptamer Chemical Structure

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VR11 aptamer Related Antibodies

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TNFRSF1A/CD120a TNFRSF3/CD18 TNFRSF4 TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF7/CD27 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF12A/TWEAK TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

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nNOS iNOS eNOS

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Description

VR11 aptamer is a DNA-based TNF-α inhibitor with a KD of 7.0 nM. VR11 aptamer prevents TNFα-induced apoptosis and NO production. VR11 aptamer has non-immunogenicity and does not raise immune responses when injected intraperitoneally into C57BL/6 mice model. VR11 aptamer can be used for inflammatory diseases research[1].

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[VR11 aptamer]
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Purity & Documentation
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VR11 aptamer Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VR11 aptamerTNF ReceptorApoptosisNO SynthaseTumor Necrosis Factor ReceptorTNFRNitric oxide synthasesNOSInhibitorTNF-αDNA-basednon-immunogenicityInflammatory diseasesinhibitorinhibit

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