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  3. Biotinylated Proteins
  4. IFNAR1 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi)

IFNAR1 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi)

Cat. No.: HY-P703993
Handling Instructions Technical Support

IFNAR1 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi) is the recombinant cynomolgus-derived IFNAR1 protein, expressed by HEK293, with C-Avi & C-His tag.

For research use only. We do not sell to patients.

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Description

IFNAR1 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi) is the recombinant cynomolgus-derived IFNAR1 protein, expressed by HEK293, with C-Avi & C-His tag.
Background

IFNAR1, together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega, and kappa). Binding of type I interferons activates the JAK-STAT signaling cascade. IFNAR1 can also function independently of IFNAR2 by forming an active IFNB1 receptor on its own and initiating a signaling cascade that does not involve the JAK-STAT pathway.
Species

Cynomolgus
Source

HEK293
Tag

C-Avi;C-8*His
Accession

A0A7N9D7J0 (A25-K437)
Gene ID

101926190
Molecular Construction
N-term
IFNAR1 (A25-K437)
Accession # A0A7N9D7J0
8*His-Avi
C-term
Protein Length

Partial
Synonyms
AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1
Predicted Molecular Mass
50.4 kDa
Molecular Weight

Approximately 75-105 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Purity

Greater than 95% as determined by Tris-Bis PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

IFNAR1 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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IFNAR1 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi)
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