Landiolol hydrochloride (Standard) (Synonyms: ONO1101 hydrochloride (Standard))

Cat. No.: HY-100607AR Purity: ≥98%: Handling Instructions
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Landiolol (ONO1101) hydrochloride (Standard) is the analytical standard of Landiolol hydrochloride (HY-100607A). This product is intended for research and analytical applications. Landiolol (ONO1101) hydrochloride is a highly selective, ultra-short-acting competitive inhibitor of β₁ adrenergic receptors. Landiolol hydrochloride specifically blocks cardiac β₁ receptors, reducing heart rate and myocardial oxygen consumption. Landiolol hydrochloride inhibits TNF-α-induced excessive mitochondrial oxygen consumption and reactive oxygen species production in a sepsis model, alleviating renal injury. Landiolol hydrochloride has little effect on cardiac ion channels (such as L-type calcium current and inward rectifier potassium current) and has a weak negative inotropic effect. Landiolol hydrochloride can be used for perioperative tachycardia control and protection studies of sepsis-related acute kidney injury.

For research use only. We do not sell to patients.

Landiolol hydrochloride (Standard) Chemical Structure

CAS No. : 144481-98-1

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Description	Landiolol (ONO1101) hydrochloride (Standard) is the analytical standard of Landiolol hydrochloride (HY-100607A). This product is intended for research and analytical applications. Landiolol (ONO1101) hydrochloride is a highly selective, ultra-short-acting competitive inhibitor of β₁ adrenergic receptors. Landiolol hydrochloride specifically blocks cardiac β₁ receptors, reducing heart rate and myocardial oxygen consumption. Landiolol hydrochloride inhibits TNF-α-induced excessive mitochondrial oxygen consumption and reactive oxygen species production in a sepsis model, alleviating renal injury. Landiolol hydrochloride has little effect on cardiac ion channels (such as L-type calcium current and inward rectifier potassium current) and has a weak negative inotropic effect. Landiolol hydrochloride can be used for perioperative tachycardia control and protection studies of sepsis-related acute kidney injury.
Molecular Weight	546.05
Formula	C₂₅H₄₀ClN₃O₈
CAS No.	144481-98-1
SMILES	O=C(OC[C@H]1OC(C)(C)OC1)CCC2=CC=C(OC[C@@H](O)CNCCNC(N3CCOCC3)=O)C=C2.[H]Cl
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Landiolol hydrochloride (Standard) Related Classifications

Inflammation/Immunology Endocrinology Cardiovascular Disease

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Landiolol hydrochloride (Standard)144481-98-1ONO1101 hydrochloride (Standard)Reference StandardsAdrenergic ReceptorCalcium ChannelPotassium ChannelReactive Oxygen SpeciesBeta ReceptorCa2+ channelsCa channelsKcsAInhibitorinhibitorinhibit

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Landiolol hydrochloride (Standard) (Synonyms: ONO1101 hydrochloride (Standard))

Product Information

Purity & Documentation

Customer Review

Landiolol hydrochloride (Standard) Related Classifications

Molarity Calculator

Dilution Calculator