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  4. alpha COP I Antibody (YA2105)

alpha COP I Antibody (YA2105)

Cat. No.: HY-P82360
User Guide for Antibodies Technical Support

alpha COP I Antibody (YA2105) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2105), targeting alpha COP I, with a predicted molecular weight of 138 kDa (observed band size: 138 kDa). alpha COP I Antibody (YA2105) can be used for WB, IHC-P experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 5 - 6 weeks 4 - 5 weeks 4 - 5 weeks
50 μL Get quote 5 - 6 weeks 4 - 5 weeks 4 - 5 weeks
100 μL Get quote 5 - 6 weeks 4 - 5 weeks 4 - 5 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

alpha COP I Antibody (YA2105) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2105), targeting alpha COP I, with a predicted molecular weight of 138 kDa (observed band size: 138 kDa). alpha COP I Antibody (YA2105) can be used for WB, IHC-P experiment in human, mouse, rat background.

Background

alpha COP I is a component of the coatomer complex, which binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles to mediate protein transport from the ER through the Golgi to the trans Golgi network. The coatomer complex is required for Golgi membrane budding and essential for the retrograde transport of dilysine-tagged proteins from the Golgi to the ER. In mammals, coatomer recruitment is restricted to membranes associated with ADP-ribosylation factors (ARFs), and the complex also maintains Golgi structural integrity while regulating the processing, activity, and endocytic recycling of LDL receptors (by similar). Additionally, xenin stimulates exocrine pancreatic secretion, inhibits pentagastrin-stimulated acid secretion, and modulates intestinal motility by interacting with the neurotensin receptor in the gut.

Gene ID
SwissProt ID
Synonyms
Alpha COP; Alpha COPI; AlphaCOP; COP A; copA; HEP COP; Proxenin; Xenin
Molecular Weight

Predicted band size: 138 kDa; Observed band size: 138 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

-

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100

Application

WB, IHC-P

Appearance

Liquid

Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human COPA

Database
Documentation

alpha COP I Antibody (YA2105) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
alpha COP I Antibody (YA2105)
Cat. No.:
HY-P82360
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