N-BOC-DL-serine methyl ester

Cat. No.: HY-W005308 Purity: ≥98.0%: Data Sheet
COA

SDS
Handling Instructions
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N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α,β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

N-BOC-DL-serine methyl ester Chemical Structure

CAS No. : 69942-12-7

Size	Stock	Quantity
25 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
500 g	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

219.23

Formula

C₉H₁₇NO₅

CAS No.

69942-12-7

Appearance

Solid-Liquid Mixture

Color

Colorless to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 200 mg/mL (912.28 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.5614 mL	22.8071 mL	45.6142 mL
5 mM	0.9123 mL	4.5614 mL	9.1228 mL
10 mM	0.4561 mL	2.2807 mL	4.5614 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

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Data Sheet (271 KB) SDS (393 KB)

COA (247 KB) HNMR (132 KB) LCMS (105 KB)

Handling Instructions (2659 KB)

References

[1]. Yang Yongqing, et al. Method for synthesizing α,β-dehydro-α-amino acid. Patent CN105037210.

[2]. Wu Chengde, et al. Preparation of quinazolinone derivatives useful as PI3Kα inhibitors for the treatment of cancer. Patent WO2019091476.

[3]. Pastor Fernandez, et al. Preparation of tricyclic pyrolopyranopyridines as protein kinase inhibitors. Patent WO2017033019.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.5614 mL	22.8071 mL	45.6142 mL	114.0355 mL
	5 mM	0.9123 mL	4.5614 mL	9.1228 mL	22.8071 mL
	10 mM	0.4561 mL	2.2807 mL	4.5614 mL	11.4035 mL
	15 mM	0.3041 mL	1.5205 mL	3.0409 mL	7.6024 mL
	20 mM	0.2281 mL	1.1404 mL	2.2807 mL	5.7018 mL
	25 mM	0.1825 mL	0.9123 mL	1.8246 mL	4.5614 mL
	30 mM	0.1520 mL	0.7602 mL	1.5205 mL	3.8012 mL
	40 mM	0.1140 mL	0.5702 mL	1.1404 mL	2.8509 mL
	50 mM	0.0912 mL	0.4561 mL	0.9123 mL	2.2807 mL
	60 mM	0.0760 mL	0.3801 mL	0.7602 mL	1.9006 mL
	80 mM	0.0570 mL	0.2851 mL	0.5702 mL	1.4254 mL
	100 mM	0.0456 mL	0.2281 mL	0.4561 mL	1.1404 mL