2. Oligonucleotides
  3. Nucleosides and their Analogs
  4. A

A

Adenine

A (298):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19528
    SAH 979-92-0 99.89%
    SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM.
    SAH
  • HY-W040329
    2'-Deoxyadenosine 958-09-8 99.99%
    2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer.
    2'-Deoxyadenosine
  • HY-123055
    Adenosine dialdehyde 34240-05-6 ≥99.0%
    Adenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research.
    Adenosine dialdehyde
  • HY-W011552
    2'-O-Methyladenosine 2140-79-6 99.44%
    2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .
    2'-O-Methyladenosine
  • HY-113284
    Succinyladenosine 4542-23-8 99.43%
    Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency.
    Succinyladenosine
  • HY-W039442
    2′-Deoxy-2′-fluoroadenosine 64183-27-3 99.71%
    2′-Deoxy-2′-fluoroadenosine can be used for the synthesis of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP.
    2′-Deoxy-2′-fluoroadenosine
  • HY-W011725
    N-6-Methyl-2-deoxyadenosine 2002-35-9 99.83%
    N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
    N-6-Methyl-2-deoxyadenosine
  • HY-W141394
    Bz-OMe-rA 85079-00-1 99.34%
    Bz-OMe-rA is a nucleoside analog.
    Bz-OMe-rA
  • HY-W008552
    2-Iodoadenosine 35109-88-7 99.21%
    2-Iodoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
    2-Iodoadenosine
  • HY-W011125
    Bz-dA 4546-72-9
    Bz-dA (N6-Benzoyl-2'-deoxyadenosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides
    Bz-dA
  • HY-103237
    L-Adenosine 3080-29-3 99.82%
    L-Adenosine is a metabolically stable enantiomeric analog and also is a potential probe. L-Adenosine has weakly inhibitory adenosine deaminase (ADA) activity with an Ki value of 385 μM. L-Adenosine can be used for the research of adenosine uptake and accumulation.
    L-Adenosine
  • HY-131818
    5'-Amino-5'-deoxyadenosine 14365-44-7
    5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
    5'-Amino-5'-deoxyadenosine
  • HY-W016041
    2-Amino-2'-deoxyadenosine 4546-70-7 99.62%
    2-Amino-2'-deoxyadenosine is a deoxyribonucleoside used for the oligonucleotide synthesis.
    2-Amino-2'-deoxyadenosine
  • HY-W011683
    2'-Deoxyadenosine monohydrate 16373-93-6 99.89%
    2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer.
    2'-Deoxyadenosine monohydrate
  • HY-W093086
    DMT-2'-F-Bz-dA 136834-21-4 99.58%
    DMT-2'-F-Bz-dA can be used in the synthesis of nucleotides and nucleic acids.
    DMT-2'-F-Bz-dA
  • HY-154578
    N1-Methyl-2'-deoxyadenosine 60192-55-4
    N1-Methyl-2'-deoxyadenosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
    N1-Methyl-2'-deoxyadenosine
  • HY-102018
    3'-Deoxy-3'-fluoroadenosine 75059-22-2 99.29%
    3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
    3'-Deoxy-3'-fluoroadenosine
  • HY-W011548
    2-Aminoadenosine 2096-10-8 ≥98.0%
    2-Aminoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
    2-Aminoadenosine
  • HY-W013195
    8-Bromoadenosine 2946-39-6 99.68%
    8-Bromoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. 8-Bromoadenosine can quench the intrinsic fluorescence of human serum albumin (HSA) through static quenching procedure. 8-Bromoadenosine can be used to synthesize adenosine phosphate, such as Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
    8-Bromoadenosine
  • HY-111646
    N6-Etheno 2'-deoxyadenosine 68498-25-9 99.48%
    N6-Etheno 2'-deoxyadenosine is a reactive oxygen species (ROS)/reactive nitrogen species (RNS)-induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.
    N6-Etheno 2'-deoxyadenosine