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  4. Collagen XVII alpha 1 Antibody (YA2759)

Collagen XVII alpha 1 Antibody (YA2759)

Cat. No.: HY-P83014
COA User Guide for Antibodies Technical Support

Collagen XVII alpha 1 Antibody (YA2759) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Collagen XVII alpha 1.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL In-stock
50 μL In-stock
100 μL In-stock
250 μL   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Collagen XVII alpha 1 Antibody (YA2759) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Collagen XVII alpha 1.

Background

Collagen XVII alpha 1 is a protein that plays a critical role in the skin basement membrane zone, primarily involved in maintaining the structural integrity of hemidesmosomes and mediating the attachment of basal keratinocytes to the underlying basement membrane. The 120 kDa linear IgA disease antigen, a component of anchoring filaments, contributes to dermal-epidermal cohesion. Additionally, Collagen XVII alpha 1 serves as the target of autoantibodies in linear IgA bullous dermatosis.

Gene ID
SwissProt ID
Synonyms
BP180; BPA 2; BPAG2; COL17A1; Collagen 17; CollagenXVII; LAD1
Molecular Weight

Predicted band size: 150 kDa; Observed band size: 130,180 kDa

Purity

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Signal Transduction

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

Dilution Ratio

WB: 1:500-1:1000; IHC: 1:50-1:100; IF: 1:50-1:200; IP: 1:30

Application

WB, IHC-P, ICC/IF, IP

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human Collagen XVII

Database

Entrez Gene: 1308 Human ;

SwissProt: Q9UMD9 Human ;

OMIM: 619787 Human

Documentation

Collagen XVII alpha 1 Antibody (YA2759) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Collagen XVII alpha 1 Antibody (YA2759)
Cat. No.:
HY-P83014
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