2. Cytoskeleton Stem Cell/Wnt MAPK/ERK Pathway Protein Tyrosine Kinase/RTK
  3. Integrin FAK ERK
  4. VSLRGDTRG acetate

VSLRGDTRG acetate is a synthetic peptide containing the RGD motif from cadherin 17 (CDH17), which binds to α2β1 integrin and activates its signaling pathway. VSLRGDTRG acetate promotes the high-affinity conformational change of β1 integrin through the RGD motif, enhancing cell adhesion and phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. VSLRGDTRG acetate can be used in research on cancers expressing CDH17, such as colon cancer and pancreatic cancer.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

VSLRGDTRG acetate Chemical Structure

VSLRGDTRG acetate Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of VSLRGDTRG acetate:

VSLRGDTRG acetate Related Antibodies

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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Description

VSLRGDTRG acetate is a synthetic peptide containing the RGD motif from cadherin 17 (CDH17), which binds to α2β1 integrin and activates its signaling pathway. VSLRGDTRG acetate promotes the high-affinity conformational change of β1 integrin through the RGD motif, enhancing cell adhesion and phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. VSLRGDTRG acetate can be used in research on cancers expressing CDH17, such as colon cancer and pancreatic cancer[1][2].

Molecular Weight

960.05 (free base)

Formula

C38H69N15O14.xC2H4O2
Appearance

Solid

Color

White to off-white

Sequence

Val-Ser-Leu-Arg-Gly-Asp-Thr-Arg-Gly
Sequence Shortening

VSLRGDTRG
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
Purity & Documentation
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VSLRGDTRG acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VSLRGDTRGIntegrinFAKERKPTK2 protein tyrosine kinase 2PTK2Focal adhesion kinaseExtracellular signal regulated kinasescolon cancerpancreatic cancerInhibitorinhibitorinhibit

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