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  5. Transcription factor AP2 alpha Antibody (YA3441)

Transcription factor AP2 alpha Antibody (YA3441)

Cat. No.: HY-P83704
User Guide for Antibodies Technical Support

Transcription factor AP2 alpha Antibody is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3441), targeting Transcription factor AP2 alpha, with a predicted molecular weight of 48 kDa (observed band size: 48 kDa). Transcription factor AP2 alpha Antibody (YA3441) can be used for WB, IF-Cell, IHC-P experiment in human, Mouse, Rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Transcription factor AP2 alpha Antibody is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3441), targeting Transcription factor AP2 alpha, with a predicted molecular weight of 48 kDa (observed band size: 48 kDa). Transcription factor AP2 alpha Antibody (YA3441) can be used for WB, IF-Cell, IHC-P experiment in human, Mouse, Rat background.
Background

AP2 alpha is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a broad spectrum of critical biological functions, including proper development of the eye, face, body wall, limbs, and neural tube. They also suppress several genes, including MCAM/MUC18, C/EBP alpha, and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, it stimulates PITX2 P1 promoter transcription activation and associates with chromatin at the PITX2 P1 promoter region.
Gene ID
SwissProt ID
Synonyms
Activating enhancer binding protein 2 alpha antibody; Activating enhancer-binding protein 2-alpha antibody; Activator protein 2 antibody; AP 2 transcription factor antibody; AP 2alpha antibody; AP-2 antibody; AP-2 transcription factor antibody; AP2 antibody; AP2 Transcription Factor antibody; AP2-alpha antibody; AP2A_HUMAN antibody; AP2TF antibody; BOFS antibody; FLJ51761 antibody; TFAP 2 antibody; TFAP 2A antibody; TFAP2 antibody; TFAP2A antibody; Transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha) antibody; Transcription factor AP-2-alpha antibody; Transcription factor AP2 alpha antibody
Molecular Weight

Predicted band size: 48 kDa; Observed band size: 48 kDa
Purity

Affinity Purified
Subcellular Location

Nucleus.
Conjugation

Non-conjugated
Modification

Unmodified
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Monoclonal, Recombinant
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1:1,000; IHC-P: 1:200-1:1,000; IF-Cell: 1:100
Application

WB, IHC-P, IHC-F
Positive Control

JAR cell lysate, HepG2 cell lysate, SiHa cell lysate, HepG2, human breast tissue, mouse eye tissue, rat breast tissue, rat skin tissue.
Appearance

Liquid
Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

Recombinant protein within human TFAP2A aa 1-437 / 437.
Database

Entrez Gene: 7020 Human ; 21418 Mouse ;

SwissProt: P05549 Human ; P34056 Mouse ; P58197 Rat

OMIM: 113620 Human

Documentation
User Guide for Antibodies (1077 KB)

Transcription factor AP2 alpha Antibody (YA3441) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Transcription factor AP2 alpha Antibody (YA3441)
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