2. Metabolic Enzyme/Protease Anti-infection
  3. Endogenous Metabolite Fungal
  4. Heveadride

Heveadride is a fungal metabolite and an antifungal agent. Heveadride is active against various filamentous fungi and some human pathogenic yeasts. Heaveadride induces down-regulation of TNFα-induced NF-κB activity in human chronic myeloid leukemia cells with a IC50 of 82.7 μM. .

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Heveadride Chemical Structure

Heveadride Chemical Structure

CAS No. : 39595-41-0

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Heveadride Related Antibodies

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Description

Heveadride is a fungal metabolite and an antifungal agent. Heveadride is active against various filamentous fungi and some human pathogenic yeasts. Heaveadride induces down-regulation of TNFα-induced NF-κB activity in human chronic myeloid leukemia cells with a IC50 of 82.7 μM. [1][2].

In Vitro

Heveadride (Compound 2) (5 and 10 μg/disc) shows moderate inhibitory activity against filamentous fungi, and has no activity against yeast at a concentration of 5 μg/disc, while has weak activity against some yeast species at a concentration of 100 μg/disc[1].
Heveadride (Compound 4) (10-100 μM, 2 h) demonstrates dose-dependent inhibitory activity against TNFα-induced NF-κB in K562 cells[2].
Heveadride (0.1-100 μM, 8-72 h) does not significantly decrease K562 cell viability at any concentration or measured time point but reduces K562 proliferation at 100 μM[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Heveadride Related Antibodies
Molecular Weight

332.35

Formula

C18H20O6
CAS No.
SMILES

CCC[C@@H]1C2=C(C(OC2=O)=O)CCC3=C(C(OC3=O)=O)C[C@H]1CC
Structure Classification
Initial Source

Helmin thosporium heveae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Heveadride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Heveadride39595-41-0Endogenous MetaboliteFungalNonadride lactoneHelminthosporium heveaeBipolaris heveaeK562antifungalInhibitorinhibitorinhibit

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