2. Metabolic Enzyme/Protease
  3. Glycosidase
  4. Carpachromene

Carpachromene is a potent α-glucosidase enzyme inhibitor. Carpachromene ameliorates insulin resistance in HepG2 cells via modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway.

For research use only. We do not sell to patients.

Carpachromene Chemical Structure

Carpachromene Chemical Structure

CAS No. : 57498-96-1

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Based on 1 publication(s) in Google Scholar

Carpachromene Related Antibodies

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Description

Carpachromene is a potent α-glucosidase enzyme inhibitor. Carpachromene ameliorates insulin resistance in HepG2 cells via modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway[1].

In Vitro

Carpachromene (0-100 μg/mL, 48 h) exhibits cytotoxicity against HepG2, HepG2/IRM, PLC/PRF/5 and Raji cancer cell lines[1].
Carpachromene (20 μg/mL) significantly increases the protein expression ratios of IR, IRS1, PI3K, Akt, GSK3, and FoxO1 in HepG2/IRM cells[1].
Carpachromene (20 μg/mL) improves cellular glycogen synthesis in HepG2/IRM cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Carpachromene Related Antibodies
Molecular Weight

336.34

Formula

C20H16O5
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

OC1=C2C(OC(C3=CC=C(O)C=C3)=CC2=O)=CC4=C1C=CC(C)(C)O4
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
References
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Carpachromene Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Carpachromene57498-96-1GlycosidaseHepG2 cellsFicus benghalensisHepG2/IRM cellsInsulin Resistant ModelInhibitorinhibitorinhibit

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