Ctip2 Antibody (YA4479)

Ctip2 Antibody (YA4479) is a mouse-derived and non-conjugated IgG1 antibody, targeting to BCL11B. It can be applicated for IHC-P, ICC/IF, FC, ELISA assays, in the background of human.

BCL11B is a key regulator of T-lymphocyte differentiation and survival during thymocyte development in mammals. It controls hematopoietic stem cell responsiveness to chemotactic signals by modulating CCR7 and CCR9 receptor expression, directing progenitor cell migration from bone marrow to thymus. Additionally, BCL11B regulates the IL2 promoter and enhances IL2 expression in activated CD4(+) T-lymphocytes. As a tumor suppressor, it represses transcription through direct, TFCOUP2-independent binding to GC-rich response elements (by similarity). It may also function in the P53-signaling pathway (by similarity).

Q9C0K0

Predicted band size: 96 kDa; Observed band size: 140 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human

IHC: 1/200-1/1000; IF: 1/50-1/250; FC: 1/200-1/400; ELISA: 1/10000

IHC-P, ICC/IF, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Purified recombinant fragment of human BCL11B (AA: 1-150) expressed in E. Coli.