14-3-3 beta Antibody (YA1949)

Cat. No.: HY-P82204: Data Sheet User Guide for Antibodies
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14-3-3 beta Antibody (YA1949) is a non-conjugated IgG antibody, with a predicted molecular weight of 28 kDa (observed band size: 27-29 kDa). 14-3-3 beta Antibody (YA1949) can be used for WB experiment in human, rat background.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

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Description	14-3-3 beta Antibody (YA1949) is a non-conjugated IgG antibody, with a predicted molecular weight of 28 kDa (observed band size: 27-29 kDa). 14-3-3 beta Antibody (YA1949) can be used for WB experiment in human, rat background.
Background	YWHAB is an adapter protein involved in regulating a broad spectrum of both general and specialized signaling pathways. It binds to numerous partner proteins, typically by recognizing phosphoserine or phosphothreonine motifs, often resulting in modulation of the partner's activity. YWHAB acts as a negative regulator of osteogenesis. It blocks the nuclear translocation of SRPK2's phosphorylated form (mediated by AKT1) and counteracts its stimulatory effect on cyclin D1 expression, thereby inhibiting SRPK2-induced neuronal apoptosis. Additionally, it serves as a negative regulator of signaling cascades that activate MAP kinases via AKAP13.
Gene ID	7529 [NCBI]
SwissProt ID	P31946
Synonyms	YWHAB; 14-3-3 protein beta/alpha; Protein 1054; Protein kinase C inhibitor protein 1; KCIP-1
Molecular Weight	Predicted band size: 28 kDa; Observed band size: 27-29 kDa
Purity	Affinity Purified
Conjugation	Non-conjugated
Modification	Unmodified
Research Field	Neuroscience
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Rat
Dilution Ratio	WB: 1/500-1/1000
Application	WB
Appearance	Liquid
Formulation	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthetic peptide of human 14-3-3
Database	Entrez Gene: 7529 Human ; 56011 Rat SwissProt: P31946 Human ; P63104 Human ; P63101 Mouse ; OMIM: 601289 Human
Documentation	Data Sheet (232 KB) User Guide for Antibodies (1077 KB)

14-3-3 beta Antibody (YA1949) Related Classifications

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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14-3-3 beta Antibody (YA1949)

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